COMPARISON OF THE EFFECTIVENESS OF PHOSPHORUS 32 APPLICATION AND 10 MG/CC TRIAMCINOLONE ACETONIDE INTRALESIONAL INJECTION ON KELOID

• Main Authors: Hani Indrayati, Jono Hadi Agusni, Asmaja Soedarwoto, Achmad Hussein S. Kartamihardja
• Format: Article
• Language: English
• Published: Universitas Padjadjaran 2016-03-01
• Series: International Journal of Integrated Health Sciences
• Subjects: Flattening; keloid; phosphorus 32; triamcinolone acetonide
• Online Access: http://journal.fk.unpad.ac.id/index.php/ijihs/article/view/683/664
• ISSN: 2302-1381; 2338-4506

Objective: To analyze the effectiveness of phosphorus 32 (32P) application compared to 10 mg/cc triamcinolone acetonide (TA) intralesional injection in keloid. Methods: A single blind (evaluator blind) randomized clinical trial on 52 keloids was conducted during the period of May – August 2014 in Tumor and Skin Surgery Clinic, Department of Dermatovenereology and Department of Nuclear Medicine and Molecular Imaging, Dr. Hasan Sadikin General Hospital Bandung. Results: Lesions were divided into two groups with each group consisted of 26 lesions. Group A was treated with 32P application whereas group B was treated with 10 mg/cc TA intralesional injection. Flattening of the lesion of more than 50% was higher in the group treated with 32P application (76.9%) compared to the group that was treated with 10 mg/cc TA intralesional injection (57.7%) on the 8th week, but the difference was not statistically significant (p>0.05). Conclusions: Based on the statistical analysis, the application of 32P was as effective as the intralesional injection of 10 mg/cc TA for keloid lesions.