Tumor- and osteoclast-derived NRP2 in prostate cancer bone metastases

Tumor- and osteoclast-derived NRP2 in prostate cancer bone metastases

Abstract Understanding the role of neuropilin 2 (NRP2) in prostate cancer cells as well as in the bone microenvironment is pivotal in the development of an effective targeted therapy for the treatment of prostate cancer bone metastasis. We observed a significant upregulation of NRP2 in prostate canc...

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Bibliographic Details
Main Authors: Navatha Shree Polavaram, Samikshan Dutta, Ridwan Islam, Arup K. Bag, Sohini Roy, David Poitz, Jeffrey Karnes, Lorenz C. Hofbauer, Manish Kohli, Brian A. Costello, Raffael Jimenez, Surinder K. Batra, Benjamin A. Teply, Michael H. Muders, Kaustubh Datta
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-021-00136-2

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