Structural Diversity in Conserved Regions Like the DRY-Motif among Viral 7TM Receptors—A Consequence of Evolutionary Pressure?

Several herpes- and poxviruses have captured chemokine receptors from their hosts and modified these to their own benefit. The human and viral chemokine receptors belong to class A 7 transmembrane (TM) receptors which are characterized by several structural motifs like the DRY-motif in TM3 and the C...

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Bibliographic Details
Main Authors: Ann-Sofie Mølleskov Jensen, Alexander Hovard Sparre-Ulrich, Nicholas Davis-Poynter, Mette Marie Rosenkilde
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Advances in Virology
Online Access:http://dx.doi.org/10.1155/2012/231813