Survey Of Relationship Between Serum Procalcitonin And Infectious Diseases
Background and Aim: Procalcitonin is prohormone of calcitonin and is made 116 amino acids. The normal value of procalcitonin is less than 0.5 ng/ml, that if this amount exceeds, infection is indicated. This poly-peptide is a marker for the diagnosis of primary infection. Increased amounts of procalc...
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Tehran University of Medical Sciences
2011-12-01
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doaj-eec5f9be1dc84cb1a42cdf01256b72302021-10-02T01:12:05ZfasTehran University of Medical Sciencesپیاورد سلامت1735-81322008-26652011-12-0143-46066Survey Of Relationship Between Serum Procalcitonin And Infectious Diseases M RahimkhaniN EinollaniR SharifianBackground and Aim: Procalcitonin is prohormone of calcitonin and is made 116 amino acids. The normal value of procalcitonin is less than 0.5 ng/ml, that if this amount exceeds, infection is indicated. This poly-peptide is a marker for the diagnosis of primary infection. Increased amounts of procalcitonin is associated with infection; especially bacterial infections. Materials and Methods: 32 patients with liver cirrhosis and 16 healthy controls enrolled in this study were. Serum PCT levels in these subjects was measured. PCT level was measured by semi-quantitative method. Results: Patient group included 23 males and nine females with mean age of 45 years and SD= 17.44 years, the control group included 11 males and 5 females with mean age of 46 years and SD=15.5 years.The statistical analysis showed that there was significant difference between PCT levels in patients and controls (P<0.05).Furthermore PCT levels was significantly hgher in cirrhotic patients with hepatitisec background.Conclusion: Since these patients had no symptoms of infection and were hospitalized for endoscopy test and the PCT test was positive in 78.1% of cirrhotic patients ,whereas this ratio was 25% in the control group, the patients probably were infected and should be under proper treatment.http://journals.tums.ac.ir/upload_files/pdf/18278.pdfProcalcitoninCirrhosisBacterial Infection |
collection |
DOAJ |
language |
fas |
format |
Article |
sources |
DOAJ |
author |
M Rahimkhani N Einollani R Sharifian |
spellingShingle |
M Rahimkhani N Einollani R Sharifian Survey Of Relationship Between Serum Procalcitonin And Infectious Diseases پیاورد سلامت Procalcitonin Cirrhosis Bacterial Infection |
author_facet |
M Rahimkhani N Einollani R Sharifian |
author_sort |
M Rahimkhani |
title |
Survey Of Relationship Between Serum Procalcitonin And Infectious Diseases |
title_short |
Survey Of Relationship Between Serum Procalcitonin And Infectious Diseases |
title_full |
Survey Of Relationship Between Serum Procalcitonin And Infectious Diseases |
title_fullStr |
Survey Of Relationship Between Serum Procalcitonin And Infectious Diseases |
title_full_unstemmed |
Survey Of Relationship Between Serum Procalcitonin And Infectious Diseases |
title_sort |
survey of relationship between serum procalcitonin and infectious diseases |
publisher |
Tehran University of Medical Sciences |
series |
پیاورد سلامت |
issn |
1735-8132 2008-2665 |
publishDate |
2011-12-01 |
description |
Background and Aim: Procalcitonin is prohormone of calcitonin and is made 116 amino acids. The normal value of procalcitonin is less than 0.5 ng/ml, that if this amount exceeds, infection is indicated. This poly-peptide is a marker for the diagnosis of primary infection. Increased amounts of procalcitonin is associated with infection; especially bacterial infections. Materials and Methods: 32 patients with liver cirrhosis and 16 healthy controls enrolled in this study were. Serum PCT levels in these subjects was measured. PCT level was measured by semi-quantitative method. Results: Patient group included 23 males and nine females with mean age of 45 years and SD= 17.44 years, the control group included 11 males and 5 females with mean age of 46 years and SD=15.5 years.The statistical analysis showed that there was significant difference between PCT levels in patients and controls (P<0.05).Furthermore PCT levels was significantly hgher in cirrhotic patients with hepatitisec background.Conclusion: Since these patients had no symptoms of infection and were hospitalized for endoscopy test and the PCT test was positive in 78.1% of cirrhotic patients ,whereas this ratio was 25% in the control group, the patients probably were infected and should be under proper treatment. |
topic |
Procalcitonin Cirrhosis Bacterial Infection |
url |
http://journals.tums.ac.ir/upload_files/pdf/18278.pdf |
work_keys_str_mv |
AT mrahimkhani surveyofrelationshipbetweenserumprocalcitoninandinfectiousdiseases AT neinollani surveyofrelationshipbetweenserumprocalcitoninandinfectiousdiseases AT rsharifian surveyofrelationshipbetweenserumprocalcitoninandinfectiousdiseases |
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