Monitoring compliance to an experimental treatment in an asymptomatic population
Objective: To develop strategies and to monitor patient’s adherence to the follow up of the experimental treatment of secondary cholestasis in its isolate chronic form with portal hypertension. Methods: Experimental study made with 11 patients. Ursodeoxycholic acid was administered in the dosage of...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Instituto Israelita de Ensino e Pesquisa Albert Einstein
2008-09-01
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| Series: | Einstein (São Paulo) |
| Subjects: | |
| Online Access: | http://apps.einstein.br/revista/arquivos/PDF/895-Einsteinv6n3p274-7.pdf |
| Summary: | Objective: To develop strategies and to monitor patient’s adherence to the follow up of the experimental treatment of secondary cholestasis in its isolate chronic form with portal hypertension. Methods: Experimental study made with 11 patients. Ursodeoxycholic acid was administered in the dosage of 15 mg/kg/day twice a day for 45 days. Evaluation of adherence was performed using pill count strategy and interviews. Rresults: The variation during pill count had no influence on the patient’s laboratory results. Serum activity of γGT normalized during treatment, returning to increased levels after interruption of medication. Cconclusions: The strategies developed were effective presenting a significant laboratory result regarding the decrease of γGT serum activity. |
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| ISSN: | 1679-4508 |