ALT-C, a disintegrin-like Cys-rich protein from Bothrops alternatus, increases skeletal myoblast viability

ALT-C, a disintegrin-like Cys-rich protein from Bothrops alternatus, increases skeletal myoblast viability

ALT-C, an ECD motif (glutamic acid, cysteine, aspartic acid) disintegrin from Bothrops alternatus snake venom, induces α2β1 integrin-mediated signaling and neutrophil chemotaxis. In vitro, in human umbilical vein endothelial cells (HUVEC), ALT-C induces cell proliferation, thus sho...

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Bibliographic Details
Main Authors: RA Mesquita-Ferrari, CK de Moraes, KC Micocci, HS Selistre-de-Araújo
Format: Article
Language:English
Published: SciELO 2009-01-01
Series:Journal of Venomous Animals and Toxins including Tropical Diseases
Subjects:
viability
myosin heavy chain
myoblast
disintegrin
skeletal muscle
Bothrops alternatus
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992009000200013

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