Outbreak investigation of Serratia marcescens neurosurgical site infections associated with a contaminated shaving razors
Abstract Background Surgical site infection (SSI) is the most common healthcare-associated infection. We report an outbreak of neurosurgical site infections caused by Serratia marcescens after craniotomy in a tertiary care hospital. Methods Between August 6 and 21, 2018, five cases of early-onset SS...
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doaj-eee61b83d100469abc7d6640255683b82020-11-25T03:16:33ZengBMCAntimicrobial Resistance and Infection Control2047-29942020-05-01911710.1186/s13756-020-00725-6Outbreak investigation of Serratia marcescens neurosurgical site infections associated with a contaminated shaving razorsEun Jin Kim0Wan Beom Park1Jung-Ki Yoon2Won-Sang Cho3Su Jung Kim4Young Rok Oh5Kang Il Jun6Chang Kyung Kang7Pyeong Gyun Choe8Jong-Il Kim9Eun Hwa Choi10Myoung Don Oh11Nam Joong Kim12Center for Infection Control and Prevention, Seoul National University HospitalCenter for Infection Control and Prevention, Seoul National University HospitalDepartment of Internal Medicine, Seoul National University College of MedicineDepartment of Neurosurgery, Seoul National University College of MedicineCenter for Infection Control and Prevention, Seoul National University HospitalCenter for Infection Control and Prevention, Seoul National University HospitalCenter for Infection Control and Prevention, Seoul National University HospitalCenter for Infection Control and Prevention, Seoul National University HospitalCenter for Infection Control and Prevention, Seoul National University HospitalGenomic Medicine Institute, Medical Research Center, Seoul National UniversityCenter for Infection Control and Prevention, Seoul National University HospitalCenter for Infection Control and Prevention, Seoul National University HospitalCenter for Infection Control and Prevention, Seoul National University HospitalAbstract Background Surgical site infection (SSI) is the most common healthcare-associated infection. We report an outbreak of neurosurgical site infections caused by Serratia marcescens after craniotomy in a tertiary care hospital. Methods Between August 6 and 21, 2018, five cases of early-onset SSI caused by S. marcescens after craniotomy were recorded in a 1786-bed tertiary care hospital. Cultures were collected from potential environmental sources and healthcare workers. Whole-genome sequencing (WGS) was used to investigate the genetic relationships among S. marcescens isolates. Results The outbreak involved five patients; S. marcescens was isolated from the cerebrospinal fluid, pus, tissue, and blood samples from these patients. S. marcescens was also isolated from shaving razors and brushes. All S. marcescens isolates from the infected patients and razors showed the same resistance patterns on antibiotic-susceptibility tests. WGS revealed close clustering among four of five isolates from the patients and among three of four isolates from the razors. No additional patient developed S. marcescens infection after we stopped using the razors for scalp shaving. Conclusions We report an outbreak of neurosurgical site infections after craniotomy, which was associated with shaving razors contaminated by S. marcescens. Shaving scalps with razors should be avoided to prevent SSI.http://link.springer.com/article/10.1186/s13756-020-00725-6Surgical site infectionSerratia marcescensDisease outbreakWhole-genome sequencing |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Eun Jin Kim Wan Beom Park Jung-Ki Yoon Won-Sang Cho Su Jung Kim Young Rok Oh Kang Il Jun Chang Kyung Kang Pyeong Gyun Choe Jong-Il Kim Eun Hwa Choi Myoung Don Oh Nam Joong Kim |
spellingShingle |
Eun Jin Kim Wan Beom Park Jung-Ki Yoon Won-Sang Cho Su Jung Kim Young Rok Oh Kang Il Jun Chang Kyung Kang Pyeong Gyun Choe Jong-Il Kim Eun Hwa Choi Myoung Don Oh Nam Joong Kim Outbreak investigation of Serratia marcescens neurosurgical site infections associated with a contaminated shaving razors Antimicrobial Resistance and Infection Control Surgical site infection Serratia marcescens Disease outbreak Whole-genome sequencing |
author_facet |
Eun Jin Kim Wan Beom Park Jung-Ki Yoon Won-Sang Cho Su Jung Kim Young Rok Oh Kang Il Jun Chang Kyung Kang Pyeong Gyun Choe Jong-Il Kim Eun Hwa Choi Myoung Don Oh Nam Joong Kim |
author_sort |
Eun Jin Kim |
title |
Outbreak investigation of Serratia marcescens neurosurgical site infections associated with a contaminated shaving razors |
title_short |
Outbreak investigation of Serratia marcescens neurosurgical site infections associated with a contaminated shaving razors |
title_full |
Outbreak investigation of Serratia marcescens neurosurgical site infections associated with a contaminated shaving razors |
title_fullStr |
Outbreak investigation of Serratia marcescens neurosurgical site infections associated with a contaminated shaving razors |
title_full_unstemmed |
Outbreak investigation of Serratia marcescens neurosurgical site infections associated with a contaminated shaving razors |
title_sort |
outbreak investigation of serratia marcescens neurosurgical site infections associated with a contaminated shaving razors |
publisher |
BMC |
series |
Antimicrobial Resistance and Infection Control |
issn |
2047-2994 |
publishDate |
2020-05-01 |
description |
Abstract Background Surgical site infection (SSI) is the most common healthcare-associated infection. We report an outbreak of neurosurgical site infections caused by Serratia marcescens after craniotomy in a tertiary care hospital. Methods Between August 6 and 21, 2018, five cases of early-onset SSI caused by S. marcescens after craniotomy were recorded in a 1786-bed tertiary care hospital. Cultures were collected from potential environmental sources and healthcare workers. Whole-genome sequencing (WGS) was used to investigate the genetic relationships among S. marcescens isolates. Results The outbreak involved five patients; S. marcescens was isolated from the cerebrospinal fluid, pus, tissue, and blood samples from these patients. S. marcescens was also isolated from shaving razors and brushes. All S. marcescens isolates from the infected patients and razors showed the same resistance patterns on antibiotic-susceptibility tests. WGS revealed close clustering among four of five isolates from the patients and among three of four isolates from the razors. No additional patient developed S. marcescens infection after we stopped using the razors for scalp shaving. Conclusions We report an outbreak of neurosurgical site infections after craniotomy, which was associated with shaving razors contaminated by S. marcescens. Shaving scalps with razors should be avoided to prevent SSI. |
topic |
Surgical site infection Serratia marcescens Disease outbreak Whole-genome sequencing |
url |
http://link.springer.com/article/10.1186/s13756-020-00725-6 |
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