Testing gene-environment interactions for rare and/or common variants in sequencing association studies.
The risk of many complex diseases is determined by a complex interplay of genetic and environmental factors. Advanced next generation sequencing technology makes identification of gene-environment (GE) interactions for both common and rare variants possible. However, most existing methods focus on t...
Main Authors: | Zihan Zhao, Jianjun Zhang, Qiuying Sha, Han Hao |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0229217 |
Similar Items
-
Testing an optimally weighted combination of common and/or rare variants with multiple traits.
by: Zhenchuan Wang, et al.
Published: (2018-01-01) -
Targeted sequencing identifies novel variants in common and rare MODY genes
by: Lucas S. deSantana, et al.
Published: (2019-12-01) -
Common sequence variants affect molecular function more than rare variants?
by: Yannick Mahlich, et al.
Published: (2017-05-01) -
Family-based association test using both common and rare variants and accounting for directions of effects for sequencing data.
by: Ren-Hua Chung, et al.
Published: (2014-01-01) -
Methods to evaluate rare variants gene-age interaction for triglycerides
by: Tony Huayang Gao, et al.
Published: (2018-09-01)