Presence of Vessel Wall Hyperintensity in Unruptured Arteriovenous Malformations on Vessel Wall Magnetic Resonance Imaging: Pilot Study of AVM Vessel Wall “Enhancement”
Purpose: High-resolution vessel wall magnetic resonance imaging (VW-MRI) could provide a way to identify high risk arteriovenous malformation (AVM) features. We present the first pilot study of clinically unruptured AVMs evaluated by high-resolution VW-MRI.Methods: A retrospective review of clinical...
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doaj-ef0ba54c72574bdeacc05282b9ef50232021-07-21T08:52:47ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2021-07-011510.3389/fnins.2021.697432697432Presence of Vessel Wall Hyperintensity in Unruptured Arteriovenous Malformations on Vessel Wall Magnetic Resonance Imaging: Pilot Study of AVM Vessel Wall “Enhancement”Laura B. Eisenmenger0Jacqueline C. Junn1Daniel Cooke2Steven Hetts3Chengcheng Zhu4Kevin M. Johnson5Jesse M. Manunga6David Saloner7Christopher Hess8Helen Kim9Department of Radiology, University of Wisconsin–Madison, Madison, WI, United StatesDepartment of Radiology, Mount Sinai Hospital, New York, NY, United StatesDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United StatesDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United StatesDepartment of Radiology, University of Washington, Seattle, WA, United StatesDepartment of Medical Physics, University of Wisconsin–Madison, Madison, WI, United StatesDivision of Vascular and Endovascular Surgery, Minneapolis Heart Institute, Abbott Northwestern Hospital, Minneapolis, MN, United StatesDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United StatesDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United StatesDepartment of Anesthesia, University of California, San Francisco, San Francisco, CA, United StatesPurpose: High-resolution vessel wall magnetic resonance imaging (VW-MRI) could provide a way to identify high risk arteriovenous malformation (AVM) features. We present the first pilot study of clinically unruptured AVMs evaluated by high-resolution VW-MRI.Methods: A retrospective review of clinically unruptured AVMs with VW-MRI between January 1, 2016 and December 31, 2018 was performed documenting the presence or absence of vessel wall “hyperintensity,” or enhancement, within the nidus as well as perivascular enhancement and evidence of old hemorrhage (EOOH). The extent of nidal vessel wall “hyperintensity” was approximated into five groups: 0, 1–25, 26–50, 51–75, and 76–100%.Results: Of the nine cases, eight demonstrated at least some degree of vessel wall nidus “hyperintensity.” Of those eight cases, four demonstrated greater than 50% of the nidus with hyperintensity at the vessel wall, and three cases had perivascular enhancement adjacent to nidal vessels. Although none of the subjects had prior clinical hemorrhage/AVM rupture, of the six patients with available susceptibility weighted imaging to assess for remote hemorrhage, only two had subtle siderosis to suggest prior sub-clinical bleeds.Conclusion: Vessel wall “enhancement” occurs in AVMs with no prior clinical rupture. Additional studies are needed to further investigate the implication of these findings.https://www.frontiersin.org/articles/10.3389/fnins.2021.697432/fullarteriovenous malformationunruptured AVMvessel wall enhancementMRIvessel wall imaging |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Laura B. Eisenmenger Jacqueline C. Junn Daniel Cooke Steven Hetts Chengcheng Zhu Kevin M. Johnson Jesse M. Manunga David Saloner Christopher Hess Helen Kim |
spellingShingle |
Laura B. Eisenmenger Jacqueline C. Junn Daniel Cooke Steven Hetts Chengcheng Zhu Kevin M. Johnson Jesse M. Manunga David Saloner Christopher Hess Helen Kim Presence of Vessel Wall Hyperintensity in Unruptured Arteriovenous Malformations on Vessel Wall Magnetic Resonance Imaging: Pilot Study of AVM Vessel Wall “Enhancement” Frontiers in Neuroscience arteriovenous malformation unruptured AVM vessel wall enhancement MRI vessel wall imaging |
author_facet |
Laura B. Eisenmenger Jacqueline C. Junn Daniel Cooke Steven Hetts Chengcheng Zhu Kevin M. Johnson Jesse M. Manunga David Saloner Christopher Hess Helen Kim |
author_sort |
Laura B. Eisenmenger |
title |
Presence of Vessel Wall Hyperintensity in Unruptured Arteriovenous Malformations on Vessel Wall Magnetic Resonance Imaging: Pilot Study of AVM Vessel Wall “Enhancement” |
title_short |
Presence of Vessel Wall Hyperintensity in Unruptured Arteriovenous Malformations on Vessel Wall Magnetic Resonance Imaging: Pilot Study of AVM Vessel Wall “Enhancement” |
title_full |
Presence of Vessel Wall Hyperintensity in Unruptured Arteriovenous Malformations on Vessel Wall Magnetic Resonance Imaging: Pilot Study of AVM Vessel Wall “Enhancement” |
title_fullStr |
Presence of Vessel Wall Hyperintensity in Unruptured Arteriovenous Malformations on Vessel Wall Magnetic Resonance Imaging: Pilot Study of AVM Vessel Wall “Enhancement” |
title_full_unstemmed |
Presence of Vessel Wall Hyperintensity in Unruptured Arteriovenous Malformations on Vessel Wall Magnetic Resonance Imaging: Pilot Study of AVM Vessel Wall “Enhancement” |
title_sort |
presence of vessel wall hyperintensity in unruptured arteriovenous malformations on vessel wall magnetic resonance imaging: pilot study of avm vessel wall “enhancement” |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Neuroscience |
issn |
1662-453X |
publishDate |
2021-07-01 |
description |
Purpose: High-resolution vessel wall magnetic resonance imaging (VW-MRI) could provide a way to identify high risk arteriovenous malformation (AVM) features. We present the first pilot study of clinically unruptured AVMs evaluated by high-resolution VW-MRI.Methods: A retrospective review of clinically unruptured AVMs with VW-MRI between January 1, 2016 and December 31, 2018 was performed documenting the presence or absence of vessel wall “hyperintensity,” or enhancement, within the nidus as well as perivascular enhancement and evidence of old hemorrhage (EOOH). The extent of nidal vessel wall “hyperintensity” was approximated into five groups: 0, 1–25, 26–50, 51–75, and 76–100%.Results: Of the nine cases, eight demonstrated at least some degree of vessel wall nidus “hyperintensity.” Of those eight cases, four demonstrated greater than 50% of the nidus with hyperintensity at the vessel wall, and three cases had perivascular enhancement adjacent to nidal vessels. Although none of the subjects had prior clinical hemorrhage/AVM rupture, of the six patients with available susceptibility weighted imaging to assess for remote hemorrhage, only two had subtle siderosis to suggest prior sub-clinical bleeds.Conclusion: Vessel wall “enhancement” occurs in AVMs with no prior clinical rupture. Additional studies are needed to further investigate the implication of these findings. |
topic |
arteriovenous malformation unruptured AVM vessel wall enhancement MRI vessel wall imaging |
url |
https://www.frontiersin.org/articles/10.3389/fnins.2021.697432/full |
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