Associations of Bcl-2 rs956572 genotype groups in the structural covariance network in early-stage Alzheimer’s disease

Associations of Bcl-2 rs956572 genotype groups in the structural covariance network in early-stage Alzheimer’s disease

Abstract Background Alzheimer’s disease (AD) is a complex neurodegenerative disease, and genetic differences may mediate neuronal degeneration. In humans, a single-nucleotide polymorphism in the B-cell chronic lymphocytic leukemia/lymphoma-2 (Bcl-2) gene, rs956572, has been found to significantly mo...

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Bibliographic Details
Main Authors: Chiung-Chih Chang, Ya-Ting Chang, Chi-Wei Huang, Shih-Jen Tsai, Shih-Wei Hsu, Shu-Hua Huang, Chen-Chang Lee, Wen-Neng Chang, Chun-Chung Lui, Chia-Yi Lien
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Alzheimer’s Research & Therapy
Subjects:
Anatomical structural covariance
Default mode network
Posterior cingulate cortex
Executive control network
Bcl-2
Polymorphism
Online Access:http://link.springer.com/article/10.1186/s13195-018-0344-4

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