Genome-wide DNA hypermethylation and homocysteine increase a risk for myopia

AIM: To test for the association between genome-wide methylation and myopia in human and mice. METHODS: Long interspersed nucleotide element 1 (LINE-1) methylation levels were used to surrogate genome-wide methylation level. We first tested for the association between high myopia (<-6 D) and LIN...

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Bibliographic Details
Main Authors: Edward Hsi, Yung-Song Wang, Chia-Wei Huang, Ming-Lung Yu, Suh-Hang Hank Juo, Chung-Ling Liang
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2019-01-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.cn/en_publish/2019/1/20190106.pdf