Alteration of the Total Cellular Glycome during Late Differentiation of Chondrocytes

Alteration of the Total Cellular Glycome during Late Differentiation of Chondrocytes

In normal articular cartilage, chondrocytes do not readily proliferate or terminally differentiate, and exhibit a low level of metabolism. Hypertrophy-like changes of chondrocytes have been proposed to play a role in the pathogenesis of osteoarthritis by inducing protease-mediated cartilage degradat...

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Bibliographic Details
Main Authors: Kentaro Homan, Hisatoshi Hanamatsu, Jun-ichi Furukawa, Kazue Okada, Ikuko Yokota, Tomohiro Onodera, Norimasa Iwasaki
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:International Journal of Molecular Sciences
Subjects:
chondrocyte hypertrophy
glycomics
glycoconjugate
glycosphingolipid
glycosaminoglycan
Online Access:https://www.mdpi.com/1422-0067/20/14/3546

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