Germ-free mice exhibit profound gut microbiota-dependent alterations of intestinal endocannabinoidome signaling

Germ-free mice exhibit profound gut microbiota-dependent alterations of intestinal endocannabinoidome signaling

The gut microbiota is a unique ecosystem of microorganisms interacting with the host through several biochemical mechanisms. The endocannabinoidome (eCBome), a complex signaling system including the endocannabinoid system, approximately 50 receptors and metabolic enzymes, and more than 20 lipid medi...

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Bibliographic Details
Main Authors: Claudia Manca, Besma Boubertakh, Nadine Leblanc, Thomas Deschênes, Sebastien Lacroix, Cyril Martin, Alain Houde, Alain Veilleux, Nicolas Flamand, Giulio G. Muccioli, Frédéric Raymond, Patrice D. Cani, Vincenzo Di Marzo, Cristoforo Silvestri
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Journal of Lipid Research
Subjects:
endocannabinoids
gut microbiome
germ-free phenotype
intestine
fecal microbiota transplant
gene expression
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520300171

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