Mitochondrial Protein PGAM5 Regulates Mitophagic Protection against Cell Necroptosis.
Necroptosis as a molecular program, rather than simply incidental cell death, was established by elucidating the roles of receptor interacting protein (RIP) kinases 1 and 3, along with their downstream partner, mixed lineage kinase-like domain protein (MLKL). Previous studies suggested that phosphog...
Main Authors: | Wei Lu, Junhui Sun, Jeong Seon Yoon, Yan Zhang, Lixin Zheng, Elizabeth Murphy, Mark P Mattson, Michael J Lenardo |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4725845?pdf=render |
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