The Occurrence and Contribution of Germline BRCA1/2 Sequence Alterations in Iranian Patients With Breast Cancer

Background: Breast cancer is the most common form of hereditary cancer worldwide and is an important cause of morbidity and mortality. Approximately 5-10% of breast and ovarian cancers are due to the highly penetrating germline mutations in cancer predisposing genes. Two genes, BRCA1 and BRCA2, acco...

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Bibliographic Details
Main Authors: Zeinali S, Sharafi Farzad M, Sharifi Z, Vahidi M, Shahab Movahead Z, Harriry Z, Salehi R, Fallah MS, Sirati F, Nafissi N, Keshavarzi F
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2011-12-01
Series:Tehran University Medical Journal
Subjects:
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/19562.pdf&manuscript_id=19562

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