Development of immunohistochemistry and in situ hybridisation for the detection of SARS-CoV and SARS-CoV-2 in formalin-fixed paraffin-embedded specimens

Abstract The rapid emergence of SARS-CoV-2, the causative agent of COVID-19, and its dissemination globally has caused an unprecedented strain on public health. Animal models are urgently being developed for SARS-CoV-2 to aid rational design of vaccines and therapeutics. Immunohistochemistry and in...

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Bibliographic Details
Main Authors: Fabian Z. X. Lean, Mart M. Lamers, Samuel P. Smith, Rebecca Shipley, Debby Schipper, Nigel Temperton, Bart L. Haagmans, Ashley C. Banyard, Kevin R. Bewley, Miles W. Carroll, Sharon M. Brookes, Ian Brown, Alejandro Nuñez
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78949-0