Involvement of bone marrow with intravascular large B-cell lymphoma
Intravascular large B-cell lymphoma (IX/LBd) is a rare subtype of extranodal large B-cell lymphoma characterized by a selective proliferation of lymphoma cells within the lumina of vessels. We report a case of an 86-year-old man who presented with fever, shortness of breath and altered mental status...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2010-01-01
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| Series: | Hematology/Oncology and Stem Cell Therapy |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1658387610500554 |
| Summary: | Intravascular large B-cell lymphoma (IX/LBd) is a rare subtype of extranodal large B-cell lymphoma characterized by a selective proliferation of lymphoma cells within the lumina of vessels. We report a case of an 86-year-old man who presented with fever, shortness of breath and altered mental status. the diagnosis of IVLBCL was confirmed on a bone trephine biopsy that revealed positivity of cD20 and PAX5 immunohistochemical staining of lymphoma cells confined within the lumina of vessels. the patient had a rapidly deteriorating clinical course with a fatal outcome even before the specific treatment for the underlying disease was commenced. |
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| ISSN: | 1658-3876 |