Regulation of Ubx expression by epigenetic enhancer silencing in response to Ubx levels and genetic variation.

For gene products that must be present in cells at defined concentrations, expression levels must be tightly controlled to ensure robustness against environmental, genetic, and developmental noise. By studying the regulation of the concentration-sensitive Drosophila melanogaster Hox gene Ultrabithor...

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Bibliographic Details
Main Authors: Michael A Crickmore, Vikram Ranade, Richard S Mann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2726431?pdf=render