Relation between DNA damage measured by comet assay and OGG1 Ser326Cys polymorphism in antineoplastic drugs biomonitoring

Relation between DNA damage measured by comet assay and OGG1 Ser326Cys polymorphism in antineoplastic drugs biomonitoring

Antineoplastic drugs are hazardous chemical agents used mostly in the treatment of patients with cancer, however health professionals that handle and administer these drugs can become exposed and develop DNA damage. Comet assay is a standard method for assessing DNA damage in human biomonitoring and...

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Bibliographic Details
Main Authors: Carina Ladeira, Susana Viegas, Mário Pádua, Elisabete Carolino, Manuel C. Gomes, Miguel Brito
Format: Article
Language:English
Published: AIMS Press 2015-09-01
Series:AIMS Molecular Science
Subjects:
DNA damage
Comet assay
OGG1 polymorphism
antineoplastic drugs
occupational exposure
biomonitoring
Online Access:http://www.aimspress.com/article/10.3934/genet.2015.3.204

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