INO80 exchanges H2A.Z for H2A by translocating on DNA proximal to histone dimers
Chromatin remodellers usually mobilize or disassemble nucleosomes by translocating along the nucleosomal DNA at the H3-H4 interface. Here, the authors provide evidence chromatin remodeller INO80 translocates along DNA at the H2A-H2B interface and displaces DNA from the surface of H2A-H2B.
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2017-06-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms15616 |
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doaj-efde14d4e3754f9bbcffa95733e77a872021-05-11T07:33:29ZengNature Publishing GroupNature Communications2041-17232017-06-018111210.1038/ncomms15616INO80 exchanges H2A.Z for H2A by translocating on DNA proximal to histone dimersSandipan Brahma0Maheshi I. Udugama1Jongseong Kim2Arjan Hada3Saurabh K. Bhardwaj4Solomon G. Hailu5Tae-Hee Lee6Blaine Bartholomew7Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer CenterGraduate Program in Molecular Biology, Microbiology and Biochemistry, Southern Illinois University School of MedicineDepartment of Chemistry and the Huck Institutes of the Life Sciences, The Pennsylvania State UniversityDepartment of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer CenterDepartment of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer CenterDepartment of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer CenterDepartment of Chemistry and the Huck Institutes of the Life Sciences, The Pennsylvania State UniversityDepartment of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer CenterChromatin remodellers usually mobilize or disassemble nucleosomes by translocating along the nucleosomal DNA at the H3-H4 interface. Here, the authors provide evidence chromatin remodeller INO80 translocates along DNA at the H2A-H2B interface and displaces DNA from the surface of H2A-H2B.https://doi.org/10.1038/ncomms15616 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sandipan Brahma Maheshi I. Udugama Jongseong Kim Arjan Hada Saurabh K. Bhardwaj Solomon G. Hailu Tae-Hee Lee Blaine Bartholomew |
spellingShingle |
Sandipan Brahma Maheshi I. Udugama Jongseong Kim Arjan Hada Saurabh K. Bhardwaj Solomon G. Hailu Tae-Hee Lee Blaine Bartholomew INO80 exchanges H2A.Z for H2A by translocating on DNA proximal to histone dimers Nature Communications |
author_facet |
Sandipan Brahma Maheshi I. Udugama Jongseong Kim Arjan Hada Saurabh K. Bhardwaj Solomon G. Hailu Tae-Hee Lee Blaine Bartholomew |
author_sort |
Sandipan Brahma |
title |
INO80 exchanges H2A.Z for H2A by translocating on DNA proximal to histone dimers |
title_short |
INO80 exchanges H2A.Z for H2A by translocating on DNA proximal to histone dimers |
title_full |
INO80 exchanges H2A.Z for H2A by translocating on DNA proximal to histone dimers |
title_fullStr |
INO80 exchanges H2A.Z for H2A by translocating on DNA proximal to histone dimers |
title_full_unstemmed |
INO80 exchanges H2A.Z for H2A by translocating on DNA proximal to histone dimers |
title_sort |
ino80 exchanges h2a.z for h2a by translocating on dna proximal to histone dimers |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2017-06-01 |
description |
Chromatin remodellers usually mobilize or disassemble nucleosomes by translocating along the nucleosomal DNA at the H3-H4 interface. Here, the authors provide evidence chromatin remodeller INO80 translocates along DNA at the H2A-H2B interface and displaces DNA from the surface of H2A-H2B. |
url |
https://doi.org/10.1038/ncomms15616 |
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