Four hepatosplenic T-cell lymphoma cases of Japanese patients

Hepatosplenic T-cell lymphoma (HSTCL), a rare type of γδ T-cell lymphoma, is characterized by hepatosplenomegaly and cytopenias. It is associated with immunodeficiency and its age of onset is reportedly between the 20s and 30s. We herein report 4 Japanese HSTCL cases. Three of them, including an eld...

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Main Authors:	Hidetsugu Kawai, Hiromichi Matsushita, Ken Ohmachi, Minoru Kojima, Shinichiro Machida, Yoshiaki Ogawa, Hiroshi Kawada, Naoya Nakamura, Kiyoshi Ando
Format:	Article
Language:	English
Published:	Elsevier 2016-01-01
Series:	Leukemia Research Reports
Subjects:	Hepatosplenic T-cell lymphoma Immunodeficiency Elderly patients
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213048915300200

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spelling	doaj-efede19e8a3848818bebe9cbfb4cca752020-11-24T21:47:28ZengElsevierLeukemia Research Reports2213-04892016-01-015C3610.1016/j.lrr.2015.12.001Four hepatosplenic T-cell lymphoma cases of Japanese patientsHidetsugu Kawai0Hiromichi Matsushita1Ken Ohmachi2Minoru Kojima3Shinichiro Machida4Yoshiaki Ogawa5Hiroshi Kawada6Naoya Nakamura7Kiyoshi Ando8Department of Hematology/Oncology, Tokai University School of Medicine, Isehara, Kanagawa, JapanDepartment of Laboratory Medicine, Tokai University School of Medicine, Isehara, Kanagawa, JapanDepartment of Hematology/Oncology, Tokai University School of Medicine, Isehara, Kanagawa, JapanDepartment of Hematology/Oncology, Tokai University School of Medicine, Isehara, Kanagawa, JapanDepartment of Hematology/Oncology, Tokai University School of Medicine, Isehara, Kanagawa, JapanDepartment of Hematology/Oncology, Tokai University School of Medicine, Isehara, Kanagawa, JapanDepartment of Hematology/Oncology, Tokai University School of Medicine, Isehara, Kanagawa, JapanDepartment of Pathology, Tokai University School of Medicine, Isehara, Kanagawa, JapanDepartment of Hematology/Oncology, Tokai University School of Medicine, Isehara, Kanagawa, JapanHepatosplenic T-cell lymphoma (HSTCL), a rare type of γδ T-cell lymphoma, is characterized by hepatosplenomegaly and cytopenias. It is associated with immunodeficiency and its age of onset is reportedly between the 20s and 30s. We herein report 4 Japanese HSTCL cases. Three of them, including an elderly case that was 74 years of age, were not at adolescence. No cases had a history of immunodeficiency. All other disease phenotypes were similar to the typical HSTCL cases. These findings suggest that there are a certain proportion of HSTCL patients who presented after middle age.http://www.sciencedirect.com/science/article/pii/S2213048915300200Hepatosplenic T-cell lymphomaImmunodeficiencyElderly patients
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Hidetsugu Kawai Hiromichi Matsushita Ken Ohmachi Minoru Kojima Shinichiro Machida Yoshiaki Ogawa Hiroshi Kawada Naoya Nakamura Kiyoshi Ando
spellingShingle	Hidetsugu Kawai Hiromichi Matsushita Ken Ohmachi Minoru Kojima Shinichiro Machida Yoshiaki Ogawa Hiroshi Kawada Naoya Nakamura Kiyoshi Ando Four hepatosplenic T-cell lymphoma cases of Japanese patients Leukemia Research Reports Hepatosplenic T-cell lymphoma Immunodeficiency Elderly patients
author_facet	Hidetsugu Kawai Hiromichi Matsushita Ken Ohmachi Minoru Kojima Shinichiro Machida Yoshiaki Ogawa Hiroshi Kawada Naoya Nakamura Kiyoshi Ando
author_sort	Hidetsugu Kawai
title	Four hepatosplenic T-cell lymphoma cases of Japanese patients
title_short	Four hepatosplenic T-cell lymphoma cases of Japanese patients
title_full	Four hepatosplenic T-cell lymphoma cases of Japanese patients
title_fullStr	Four hepatosplenic T-cell lymphoma cases of Japanese patients
title_full_unstemmed	Four hepatosplenic T-cell lymphoma cases of Japanese patients
title_sort	four hepatosplenic t-cell lymphoma cases of japanese patients
publisher	Elsevier
series	Leukemia Research Reports
issn	2213-0489
publishDate	2016-01-01
description	Hepatosplenic T-cell lymphoma (HSTCL), a rare type of γδ T-cell lymphoma, is characterized by hepatosplenomegaly and cytopenias. It is associated with immunodeficiency and its age of onset is reportedly between the 20s and 30s. We herein report 4 Japanese HSTCL cases. Three of them, including an elderly case that was 74 years of age, were not at adolescence. No cases had a history of immunodeficiency. All other disease phenotypes were similar to the typical HSTCL cases. These findings suggest that there are a certain proportion of HSTCL patients who presented after middle age.
topic	Hepatosplenic T-cell lymphoma Immunodeficiency Elderly patients
url	http://www.sciencedirect.com/science/article/pii/S2213048915300200
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Four hepatosplenic T-cell lymphoma cases of Japanese patients

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