The transcriptional elongation rate regulates alternative polyadenylation in yeast
Yeast cells undergoing the diauxic response show a striking upstream shift in poly(A) site utilization, with increased use of ORF-proximal poly(A) sites resulting in shorter 3’ mRNA isoforms for most genes. This altered poly(A) pattern is extremely similar to that observed in cells containing Pol II...
Main Authors: | Joseph V Geisberg, Zarmik Moqtaderi, Kevin Struhl |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-08-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/59810 |
Similar Items
-
Co-Transcriptional RNA Processing in Plants: Exploring from the Perspective of Polyadenylation
by: Jing Yang, et al.
Published: (2021-03-01) -
Alternative polyadenylation of mRNA and its role in cancer
by: Fuwen Yuan, et al.
Published: (2021-01-01) -
Genetic and pharmacological evidence for kinetic competition between alternative poly(A) sites in yeast
by: Rachael Emily Turner, et al.
Published: (2021-07-01) -
Regulation of RNA Polymerase II Transcription Initiation and Elongation by Transcription Factor TFII-I
by: Niko Linzer, et al.
Published: (2021-05-01) -
Alterations in polyadenylation and its implications for endocrine disease
by: Anders eRehfeld, et al.
Published: (2013-05-01)