Phosphorylated transducer and activator of transcription-3 (pSTAT3) immunohistochemical expression in paired primary and metastatic colorectal cancer

Phosphorylated transducer and activator of transcription-3 (pSTAT3) immunohistochemical expression in paired primary and metastatic colorectal cancer

Background: Signal Transducer and Activator of Transcription-3 (STAT3) mediates cellular functions. We assessed the IHC expression of phosphorylated STAT3 (pSTAT3) in paired primary tumors and liver metastases in patients with advanced stage colorectal cancer (CRC). Methods: We included patients wit...

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Bibliographic Details
Main Authors: Esmeralda C. Marginean, Joanna Gotfrit, Horia Marginean, Daniel W. Yokom, Justin J. Bateman, Manijeh Daneshmand, Shelly Sud, Allen M. Gown, Derek Jonker, Timothy Asmis, Rachel A. Goodwin
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Translational Oncology
Subjects:
Phosphorylated signal transducer and activator of transcription-3 (pSTAT3)
Primary cancer paired with liver metastasis
Colorectal cancer
Immunohistochemistry
Clinical decisions
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523320304885

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