Zika virus crosses an in vitro human blood brain barrier model

Zika virus crosses an in vitro human blood brain barrier model

Abstract Zika virus (ZIKV) is a flavivirus that is highly neurotropic causing congenital abnormalities and neurological damage to the central nervous systems (CNS). In this study, we used a human induced pluripotent stem cell (iPSC)-derived blood brain barrier (BBB) model to demonstrate that ZIKV ca...

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Bibliographic Details
Main Authors: Judie B. Alimonti, Maria Ribecco-Lutkiewicz, Caroline Sodja, Anna Jezierski, Danica B. Stanimirovic, Qing Liu, Arsalan S. Haqqani, Wayne Conlan, Mahmud Bani-Yaghoub
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Fluids and Barriers of the CNS
Subjects:
Zika virus
Brain endothelial cells
Blood–brain barrier model
iPSC
AXL
Neural progenitors
Online Access:http://link.springer.com/article/10.1186/s12987-018-0100-y

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