Murine Typhus Infection in Pregnancy: Case Series and Literature Review
Murine typhus is a flea-borne disease of worldwide distribution with a recent reemergence in the United States of America. There are limited data about the presentation, treatment, and outcomes in the pregnant population. We report on two cases of murine typhus during pregnancy and review the litera...
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doaj-f00bdcc780ac424f96c7ffb218f1d3c92021-02-19T00:02:34ZengMDPI AGPathogens2076-08172021-02-011021921910.3390/pathogens10020219Murine Typhus Infection in Pregnancy: Case Series and Literature ReviewMelinda B. Tanabe0Lucas S. Blanton1Mauricio La Rosa2Camille M. Webb3Department of Medicine, Division of Infectious Diseases, University of Texas Medical Branch, Galveston, TX 77555, USADepartment of Medicine, Division of Infectious Diseases, University of Texas Medical Branch, Galveston, TX 77555, USADepartment of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of Texas Medical Branch, Galveston, TX 77555, USADepartment of Medicine, Division of Infectious Diseases, University of Texas Medical Branch, Galveston, TX 77555, USAMurine typhus is a flea-borne disease of worldwide distribution with a recent reemergence in the United States of America. There are limited data about the presentation, treatment, and outcomes in the pregnant population. We report on two cases of murine typhus during pregnancy and review the literature to compile previously reported cases. A comprehensive search was performed via the PubMed database for published articles between 1990 and 2020. Seven articles met the criteria of symptomatic pregnant murine typhus infection. A total of 37 patients were identified. Patients frequently presented with a prolonged duration of fevers prior to presentation, headache, and elevated hepatic transaminases. The diagnosis was predominantly based on serology. Treatment varied. Overall, the pregnancy outcome was favorable. Murine typhus can mimic other pregnancy-related pathologies. More exclusive and large-scale studies are needed to learn more of murine typhus during pregnancy.https://www.mdpi.com/2076-0817/10/2/219murine typhusendemic typhusopossumspregnancydoxycyclineazithromycin |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Melinda B. Tanabe Lucas S. Blanton Mauricio La Rosa Camille M. Webb |
spellingShingle |
Melinda B. Tanabe Lucas S. Blanton Mauricio La Rosa Camille M. Webb Murine Typhus Infection in Pregnancy: Case Series and Literature Review Pathogens murine typhus endemic typhus opossums pregnancy doxycycline azithromycin |
author_facet |
Melinda B. Tanabe Lucas S. Blanton Mauricio La Rosa Camille M. Webb |
author_sort |
Melinda B. Tanabe |
title |
Murine Typhus Infection in Pregnancy: Case Series and Literature Review |
title_short |
Murine Typhus Infection in Pregnancy: Case Series and Literature Review |
title_full |
Murine Typhus Infection in Pregnancy: Case Series and Literature Review |
title_fullStr |
Murine Typhus Infection in Pregnancy: Case Series and Literature Review |
title_full_unstemmed |
Murine Typhus Infection in Pregnancy: Case Series and Literature Review |
title_sort |
murine typhus infection in pregnancy: case series and literature review |
publisher |
MDPI AG |
series |
Pathogens |
issn |
2076-0817 |
publishDate |
2021-02-01 |
description |
Murine typhus is a flea-borne disease of worldwide distribution with a recent reemergence in the United States of America. There are limited data about the presentation, treatment, and outcomes in the pregnant population. We report on two cases of murine typhus during pregnancy and review the literature to compile previously reported cases. A comprehensive search was performed via the PubMed database for published articles between 1990 and 2020. Seven articles met the criteria of symptomatic pregnant murine typhus infection. A total of 37 patients were identified. Patients frequently presented with a prolonged duration of fevers prior to presentation, headache, and elevated hepatic transaminases. The diagnosis was predominantly based on serology. Treatment varied. Overall, the pregnancy outcome was favorable. Murine typhus can mimic other pregnancy-related pathologies. More exclusive and large-scale studies are needed to learn more of murine typhus during pregnancy. |
topic |
murine typhus endemic typhus opossums pregnancy doxycycline azithromycin |
url |
https://www.mdpi.com/2076-0817/10/2/219 |
work_keys_str_mv |
AT melindabtanabe murinetyphusinfectioninpregnancycaseseriesandliteraturereview AT lucassblanton murinetyphusinfectioninpregnancycaseseriesandliteraturereview AT mauriciolarosa murinetyphusinfectioninpregnancycaseseriesandliteraturereview AT camillemwebb murinetyphusinfectioninpregnancycaseseriesandliteraturereview |
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