A Cancer-Specific Qualitative Method for Estimating the Proportion of Tumor-Infiltrating Immune Cells

A Cancer-Specific Qualitative Method for Estimating the Proportion of Tumor-Infiltrating Immune Cells

Tumor-infiltrating immune cells are important components in the tumor microenvironment (TME) and different types of these cells exert different effects on tumor development and progression; these effects depend upon the type of cancer involved. Several methods have been developed for estimating the...

Full description

Bibliographic Details
Main Authors:	Huiting Xiao, Jiashuai Zhang, Kai Wang, Kai Song, Hailong Zheng, Jing Yang, Keru Li, Rongqiang Yuan, Wenyuan Zhao, Yang Hui
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-05-01
Series:	Frontiers in Immunology
Subjects:	tumor microenvironment relative expression orderings signature genes prognosis immunotherapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.672031/full

Similar Items

Correlate tumor mutation burden with immune signatures in human cancers
by: Xiaosheng Wang, et al.
Published: (2019-01-01)

Prognostic value of tumor immune cell infiltration patterns in colon adenocarcinoma based on systematic bioinformatics analysis
by: Hao Xu, et al.
Published: (2021-07-01)

Novel immune-related genes in the tumor microenvironment with prognostic value in breast cancer
by: Wen Tan, et al.
Published: (2021-02-01)

A Tumor Progression Related 7-Gene Signature Indicates Prognosis and Tumor Immune Characteristics of Gastric Cancer
by: Fen Liu, et al.
Published: (2021-06-01)

Landscape of Immune Microenvironment Under Immune Cell Infiltration Pattern in Breast Cancer
by: Qianhui Xu, et al.
Published: (2021-08-01)

Assessing immune infiltration and the tumor microenvironment for the diagnosis and prognosis of sarcoma
by: Naiqiang Zhu, et al.
Published: (2020-12-01)

Construction and Validation of an Immune Infiltration-Related Gene Signature for the Prediction of Prognosis and Therapeutic Response in Breast Cancer
by: Yang Peng, et al.
Published: (2021-04-01)

Qualitative Analysis of Tumor-Infiltrating Lymphocytes across Human Tumor Types Reveals a Higher Proportion of Bystander CD8<sup>+</sup> T Cells in Non-Melanoma Cancers Compared to Melanoma
by: Aishwarya Gokuldass, et al.
Published: (2020-11-01)

The Pyroptosis-Related Signature Predicts Prognosis and Indicates Immune Microenvironment Infiltration in Gastric Cancer
by: Wei Shao, et al.
Published: (2021-06-01)

Identification and Validation of a Prognostic Immune-Related Alternative Splicing Events Signature for Glioma
by: Minjie Wang, et al.
Published: (2021-05-01)

MiRNA based tumor mutation burden diagnostic and prognostic prediction models for endometrial cancer
by: Nan Lu, et al.
Published: (2021-01-01)

Domatinostat favors the immunotherapy response by modulating the tumor immune microenvironment (TIME)
by: Anne Catherine Bretz, et al.
Published: (2019-11-01)

Identification of Immune Cell Infiltration Landscape and Their Prognostic Significance in Uveal Melanoma
by: Han Zhao, et al.
Published: (2021-08-01)

Tumor Microenvironment-Associated Immune-Related Genes for the Prognosis of Malignant Pleural Mesothelioma
by: Xiaoling Xu, et al.
Published: (2020-09-01)

Identification of prognostic immune-related gene signature associated with tumor microenvironment of colorectal cancer
by: Yuanyuan Wang, et al.
Published: (2021-08-01)

Seven immune‐related genes prognostic power and correlation with tumor‐infiltrating immune cells in hepatocellular carcinoma
by: Tiantian Liu, et al.
Published: (2020-10-01)

A Prognostic Microenvironment-Related Immune Signature via ESTIMATE (PROMISE Model) Predicts Overall Survival of Patients With Glioma
by: Huaide Qiu, et al.
Published: (2020-12-01)

Identification and Development of a Novel 4-Gene Immune-Related Signature to Predict Osteosarcoma Prognosis
by: Mingde Cao, et al.
Published: (2020-12-01)

Profiles of immune cell infiltration and immune-related genes in the tumor microenvironment of colorectal cancer
by: Penglei Ge, et al.
Published: (2019-10-01)

Quantitative or qualitative transcriptional diagnostic signatures? A case study for colorectal cancer
by: Qingzhou Guan, et al.
Published: (2018-01-01)

Establishment of a novel glycolysis-related prognostic gene signature for ovarian cancer and its relationships with immune infiltration of the tumor microenvironment
by: Jianlei Bi, et al.
Published: (2021-09-01)

Comprehensive Molecular Analyses of a Novel Mutational Signature Classification System with Regard to Prognosis, Genomic Alterations, and Immune Landscape in Glioma
by: Zaoqu Liu, et al.
Published: (2021-07-01)

A Prognostic Signature Based on Immunogenomic Profiling Offers Guidance for Esophageal Squamous Cell Cancer Treatment
by: Jianyao Gao, et al.
Published: (2021-02-01)

A Ferroptosis-Related Signature Robustly Predicts Clinical Outcomes and Associates With Immune Microenvironment for Thyroid Cancer
by: Mingqin Ge, et al.
Published: (2021-04-01)

Molecular and Clinicopathological Characterization of a Prognostic Immune Gene Signature Associated With MGMT Methylation in Glioblastoma
by: Liang Zhao, et al.
Published: (2021-02-01)

Analysis of Autophagy-Related Signatures Identified Two Distinct Subtypes for Evaluating the Tumor Immune Microenvironment and Predicting Prognosis in Ovarian Cancer
by: Xingyu Chen, et al.
Published: (2021-05-01)

Identification of Immune-Related Subtypes and Characterization of Tumor Microenvironment Infiltration in Bladder Cancer
by: Mengjia Huang, et al.
Published: (2021-08-01)

Identification of methylation-driven genes prognosis signature and immune microenvironment in uterus corpus endometrial cancer
by: JinHui Liu, et al.
Published: (2021-07-01)

Identification of Tumor Microenvironment-Related Alternative Splicing Events to Predict the Prognosis of Endometrial Cancer
by: Xuan Liu, et al.
Published: (2021-04-01)

Characterization of the m6A-Associated Tumor Immune Microenvironment in Prostate Cancer to Aid Immunotherapy
by: Zezhen Liu, et al.
Published: (2021-08-01)

Unraveling tumour microenvironment heterogeneity in nasopharyngeal carcinoma identifies biologically distinct immune subtypes predicting prognosis and immunotherapy responses
by: Yu-Pei Chen, et al.
Published: (2021-01-01)

Immune microenvironments differ in immune characteristics and outcome of glioblastoma multiforme
by: Botao Zhang, et al.
Published: (2019-06-01)

Immune and stromal scoring system associated with tumor microenvironment and prognosis: a gene-based multi-cancer analysis
by: Zihang Zeng, et al.
Published: (2021-08-01)

Prognosis and Characterization of Immune Microenvironment in Acute Myeloid Leukemia Through Identification of an Autophagy-Related Signature
by: Denggang Fu, et al.
Published: (2021-05-01)

The effect of a novel glycolysis-related gene signature on progression, prognosis and immune microenvironment of renal cell carcinoma
by: Fangshi Xu, et al.
Published: (2020-12-01)

A signature of 17 immune-related gene pairs predicts prognosis and immune status in HNSCC patients
by: Pan Jiang, et al.
Published: (2021-01-01)

Integrated analyses of m1A regulator-mediated modification patterns in tumor microenvironment-infiltrating immune cells in colon cancer
by: Yuzhen Gao, et al.
Published: (2021-01-01)

Modulation of Immune Infiltration of Ovarian Cancer Tumor Microenvironment by Specific Subpopulations of Fibroblasts
by: Ji Wang, et al.
Published: (2020-10-01)

Identification of a Novel Immune Landscape Signature for Predicting Prognosis and Response of Endometrial Carcinoma to Immunotherapy and Chemotherapy
by: Jinhui Liu, et al.
Published: (2021-07-01)

Survival prediction and response to immune checkpoint inhibitors: A prognostic immune signature for hepatocellular carcinoma
by: Ying Xu, et al.
Published: (2021-01-01)