Birdshot Chorioretinopathy treated with dexamethasone intravitreal implant and a biologic response modifier: a successful management

• Main Authors: Ricardo Evangelista Marrocos de Aragao, Ieda Maria Alexandre Barreira, Cristina Muccioli, Francisco Holanda Oliveira Neto, Barbara Lorena Alves Arrais, Francisco George Magalhães de Oliveira, Gustavo Jose Arruda Mendes Carneiro
• Format: Article
• Language: English
• Published: Universidade Federal do Ceará 2017-12-01
• Series: Revista de Medicina da UFC
• Subjects: Uveitis. Birdshot chorioretinopathy. HLA-A29. Retinal vasculitis. Anti-inflammatory agents.
• Online Access: http://periodicos.ufc.br/revistademedicinadaufc/article/view/20133

Birdshot chorioretinopathy is an organ-specific, potentially blinding chronic of bilateral inflammation of the posterior eye segment. It is seen mainly in persons who have the HLA-A29 haplotype. The diagnosis remains clinical and is based in his hallmark, which is the presence of multiples white dots throughout the fundus, resembling a shotgun pattern. The immune mechanisms involved in its pathogenesis remains unclear and the long-term outcome is guarded. However, the use of immunosuppressive agents and newer therapies demonstrated control of the inflammation and is a hope mainly in refractory cases. We report a case of Birdshot chorioretinopathy treated successfully with steroids and immunosuppressive agents.