Complement-Activating Capacity of Autoantibodies Correlates With Disease Activity in Bullous Pemphigoid Patients

Complement-Activating Capacity of Autoantibodies Correlates With Disease Activity in Bullous Pemphigoid Patients

Background: Bullous pemphigoid is a subepidermal blistering skin disease, associated with autoantibodies to hemidesmosomal proteins, complement activation at the dermal-epidermal junction, and dermal granulocyte infiltration. Clinical and experimental laboratory findings support conflicting hypothes...

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Bibliographic Details
Main Authors: Roxana M. Chiorean, Adrian Baican, Mayson B. Mustafa, Annette Lischka, Daniel-Corneliu Leucuta, Vasile Feldrihan, Michael Hertl, Cassian Sitaru
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
bullous pemphigoid
complement-activating capacity of autoantibodies
complement-binding test
disease activity
ABSIS
BPDAI
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02687/full

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