Genome-wide modeling of transcription preinitiation complex disassembly mechanisms using ChIP-chip data.
Apparent occupancy levels of proteins bound to DNA in vivo can now be routinely measured on a genomic scale. A challenge in relating these occupancy levels to assembly mechanisms that are defined with biochemically isolated components lies in the veracity of assumptions made regarding the in vivo sy...
Main Authors: | Eric Samorodnitsky, B Franklin Pugh |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-04-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2848545?pdf=render |
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