Exploratory investigation of Bacteroides fragilis transcriptional response during in vitro exposure to subinhibitory concentration of metronidazole

Exploratory investigation of Bacteroides fragilis transcriptional response during in vitro exposure to subinhibitory concentration of metronidazole

Bacteroides fragilis, member from commensal gut microbiota, is an important pathogen associated to endogenous infections and metronidazole remains a valuable antibiotic for the treatment of these infections, although bacterial resistance is widely reported. Considering the need of a better understan...

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Bibliographic Details
Main Authors: Michele Cristine Ribeiro Freitas, Juliana Alves Resende, Alessandra Ferreira-Machado, Guadalupe Saji, Ana Tereza Vasconcelos, Vânia da Silva, Marisa Nicolas, Cláudio Galuppo Diniz
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Microbiology
Subjects:
Bacteroides fragilis
Metronidazole
RNA-Seq
Subinhibitory concentration
K-means clustering analysis.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01465/full

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