Knockdown of LncRNA MAPT-AS1 inhibites proliferation and migration and sensitizes cancer cells to paclitaxel by regulating MAPT expression in ER-negative breast cancers

Knockdown of LncRNA MAPT-AS1 inhibites proliferation and migration and sensitizes cancer cells to paclitaxel by regulating MAPT expression in ER-negative breast cancers

Abstract Background MAPT-AS1, a long non-coding RNA, has not been reported in any previous research about its function in cancers. In this study, we investigated the role of MAPT-AS1 in the progression and paclitaxel resistance in breast cancer, and the regulation between MAPT-AS1 and its natural co...

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Bibliographic Details
Main Authors: Yiyuan Pan, Yiqi Pan, Yue Cheng, Fan Yang, Zhihan Yao, Ouchen Wang
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Cell & Bioscience
Subjects:
MAPT-AS1
Cell growth
Invasiveness
Paclitaxel resistance
MAPT
Natural antisense transcript
Online Access:http://link.springer.com/article/10.1186/s13578-018-0207-5

Internet

http://link.springer.com/article/10.1186/s13578-018-0207-5

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