Fungemia and Other Fungal Infections Associated with Use of Saccharomyces boulardii Probiotic Supplements
Because of widespread use of probiotics, their safety must be guaranteed. We assessed use of Saccharomyces boulardii probiotic yeast from medical records for patients who had Saccharomyces fungemia or other clinical Saccharomyces culture findings. We evaluated all Saccharomyces sp. findings at 5 un...
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Centers for Disease Control and Prevention
2021-08-01
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doaj-f0a0a2a281c14d86ab31638e6162486a2021-07-21T17:58:08ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592021-08-012782043205110.3201/eid2708.210018Fungemia and Other Fungal Infections Associated with Use of Saccharomyces boulardii Probiotic SupplementsJuha RannikkoVille HolmbergMatti KarppelinPertti ArvolaReetta HuttunenEero MattilaNiina KerttulaTeija PuhtoÜlle TammIrma KoivulaRisto VuentoJaana SyrjänenUlla Hohenthal Because of widespread use of probiotics, their safety must be guaranteed. We assessed use of Saccharomyces boulardii probiotic yeast from medical records for patients who had Saccharomyces fungemia or other clinical Saccharomyces culture findings. We evaluated all Saccharomyces sp. findings at 5 university hospitals in Finland during 2009–2018. We found 46 patients who had Saccharomyces fungemia; at least 20 (43%) were using S. boulardii probiotic. Compared with a control group that had bacteremia or candidemia, the odds ratio for use of an S. boulardii probiotic was 14 (95% CI 4–44). Of 1,153 nonblood culture findings, the history for 125 patients was checked; at least 24 (19%) were using the probiotic (odds ratio 10, 95% CI 3–32). This study adds to published fungemia cases linked to use of S. boulardii probiotic and sheds light on the scale of nonblood Saccharomyces culture findings that are also linked to use of this probiotic. https://wwwnc.cdc.gov/eid/article/27/8/21-0018_articlefungemiafungal infectionsfungiSaccharomyces boulardiiyeastprobiotic supplements |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Juha Rannikko Ville Holmberg Matti Karppelin Pertti Arvola Reetta Huttunen Eero Mattila Niina Kerttula Teija Puhto Ülle Tamm Irma Koivula Risto Vuento Jaana Syrjänen Ulla Hohenthal |
spellingShingle |
Juha Rannikko Ville Holmberg Matti Karppelin Pertti Arvola Reetta Huttunen Eero Mattila Niina Kerttula Teija Puhto Ülle Tamm Irma Koivula Risto Vuento Jaana Syrjänen Ulla Hohenthal Fungemia and Other Fungal Infections Associated with Use of Saccharomyces boulardii Probiotic Supplements Emerging Infectious Diseases fungemia fungal infections fungi Saccharomyces boulardii yeast probiotic supplements |
author_facet |
Juha Rannikko Ville Holmberg Matti Karppelin Pertti Arvola Reetta Huttunen Eero Mattila Niina Kerttula Teija Puhto Ülle Tamm Irma Koivula Risto Vuento Jaana Syrjänen Ulla Hohenthal |
author_sort |
Juha Rannikko |
title |
Fungemia and Other Fungal Infections Associated with Use of Saccharomyces boulardii Probiotic Supplements |
title_short |
Fungemia and Other Fungal Infections Associated with Use of Saccharomyces boulardii Probiotic Supplements |
title_full |
Fungemia and Other Fungal Infections Associated with Use of Saccharomyces boulardii Probiotic Supplements |
title_fullStr |
Fungemia and Other Fungal Infections Associated with Use of Saccharomyces boulardii Probiotic Supplements |
title_full_unstemmed |
Fungemia and Other Fungal Infections Associated with Use of Saccharomyces boulardii Probiotic Supplements |
title_sort |
fungemia and other fungal infections associated with use of saccharomyces boulardii probiotic supplements |
publisher |
Centers for Disease Control and Prevention |
series |
Emerging Infectious Diseases |
issn |
1080-6040 1080-6059 |
publishDate |
2021-08-01 |
description |
Because of widespread use of probiotics, their safety must be guaranteed. We assessed use of Saccharomyces boulardii probiotic yeast from medical records for patients who had Saccharomyces fungemia or other clinical Saccharomyces culture findings. We evaluated all Saccharomyces sp. findings at 5 university hospitals in Finland during 2009–2018. We found 46 patients who had Saccharomyces fungemia; at least 20 (43%) were using S. boulardii probiotic. Compared with a control group that had bacteremia or candidemia, the odds ratio for use of an S. boulardii probiotic was 14 (95% CI 4–44). Of 1,153 nonblood culture findings, the history for 125 patients was checked; at least 24 (19%) were using the probiotic (odds ratio 10, 95% CI 3–32). This study adds to published fungemia cases linked to use of S. boulardii probiotic and sheds light on the scale of nonblood Saccharomyces culture findings that are also linked to use of this probiotic.
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topic |
fungemia fungal infections fungi Saccharomyces boulardii yeast probiotic supplements |
url |
https://wwwnc.cdc.gov/eid/article/27/8/21-0018_article |
work_keys_str_mv |
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