Gamma-Aminobutyric Acid Increases Erythropoietin by Activation of Citrate Cycle and Stimulation of Hypoxia-Inducible Factors Expression in Rats
Erythropoietin (EPO) is the primary regulator of erythropoiesis in the mammalian fetus and adult. Deficiency of EPO induces anemia. In this study, we investigated the effect of gamma-aminobutyric acid (GABA) on serum EPO levels and erythropoiesis in rats. Expression levels of <i>Epo</i>-...
Main Authors: | Keun-Tae Park, Jong-Kwon Han, Seong Jin Kim, Young-Hee Lim |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-04-01
|
Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/10/4/595 |
Similar Items
-
APPLICATION OF ERYTHROPOIETIN THETA IN THERAPY OF ANEMIA IN ONCOLOGIC PATIENTS
by: O. A. GLADKOV, et al.
Published: (2016-12-01) -
Midazolam inhibits the hypoxia-induced up-regulation of erythropoietin in the central nervous system
by: Matsuyama, Tomonori
Published: (2015) -
Expression of erythropoietin and its receptor increases in colonic neoplastic progression: The role of hypoxia in tumorigenesis
by: Zoltan Gombos, et al.
Published: (2011-01-01) -
Erythropoietin production by the kidney and the liver in response to severe hypoxia evaluated by Western blotting with deglycosylation
by: Yukiko Yasuoka, et al.
Published: (2020-06-01) -
Upregulation of erythropoietin and erythropoietin receptor in castration-resistant progression of prostate cancer
by: Chen Ye, et al.
Published: (2020-01-01)