Decoupling the Roles of Cell Shape and Mechanical Stress in Orienting and Cueing Epithelial Mitosis

Decoupling the Roles of Cell Shape and Mechanical Stress in Orienting and Cueing Epithelial Mitosis

Summary: Distinct mechanisms involving cell shape and mechanical force are known to influence the rate and orientation of division in cultured cells. However, uncoupling the impact of shape and force in tissues remains challenging. Combining stretching of Xenopus tissue with mathematical methods of...

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Bibliographic Details
Main Authors: Alexander Nestor-Bergmann, Georgina A. Stooke-Vaughan, Georgina K. Goddard, Tobias Starborg, Oliver E. Jensen, Sarah Woolner
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719301391

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