ER-positive breast cancer cells are poised for RET-mediated endocrine resistance.

ER-positive breast cancer cells are poised for RET-mediated endocrine resistance.

The RET tyrosine kinase signaling pathway is involved in the development of endocrine resistant ER+ breast cancer. However, we know little about how ER+ cells activate RET signaling and initiate an endocrine resistant phenotype. Here we show that both ER+ endocrine resistant and sensitive breast can...

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Bibliographic Details
Main Authors: Sachi Horibata, Edward J Rice, Chinatsu Mukai, Brooke A Marks, Kelly Sams, Hui Zheng, Lynne J Anguish, Scott A Coonrod, Charles G Danko
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5880349?pdf=render

Internet

http://europepmc.org/articles/PMC5880349?pdf=render

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