A Study of the correlation between radiological and histopathological findings in intracranial lesions
Objective: This study was conducted to formulate locationwise radiologic diagnostic algorithms and assess their concordance with the final histopathological diagnosis of intracranial mass lesions to evaluate their utility in a rural setting where only basic facilities are available. Material and...
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| Format: | Article |
| Language: | English |
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Prathima Institute of Medical Sciences
2020-12-01
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| Series: | Perspectives In Medical Research |
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| Online Access: | https://www.pimr.org.in/2020-vol8-issue-3/originalarticle6_v1.pdf |
| Summary: | Objective: This study was conducted to formulate locationwise radiologic diagnostic algorithms and assess their
concordance with the final histopathological diagnosis of
intracranial mass lesions to evaluate their utility in a rural
setting where only basic facilities are available.
Material and Method: In present study seventy two cases were
analyzed.Histopathological evaluation was done from biopsy
sample sent in formalin, tissue processing was done by
standard procedure, tissue sections were routinely stained by
H&E, immunohistochemical examination was performed in
case of histopathological discrepancies. Radiological findings
were correlated with histopathological diagnosis and
concordances were calculated.
Statistical Analysis: Frequencies and crosstabs were used for
calculation.
Result: This was a study of seventy-two patients with age
ranging from 9months to 65 years. In these entire 72 cases,
male patients were 42(58%), female patients were 30(42%).
M: F was 1.38:1. Most of patient presented with headache,
and frontal lobe was the most common location. In all these
lesions, 88.8% cases were neoplastic lesions. Among all
neoplastic lesions, 52.7% were malignant tumors and 34.7%
were benign tumors. Among all malignant tumors,
Astrocytoma was the most common malignant
tumor.Meningioma was the second most commonly
encountered lesion. In the present study radiological and
histopathological correlation was present in84.7% of cases. IHC
was performed wherever needed, to support diagnosis.
Conclusion: Radiological investigations are reliable diagnostic
tools for space occupying central nervous system lesions, but
histopathology is still the gold standard. So multidisciplinary
approach is the ideal approach for space occupying lesions of
central nervous system |
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| ISSN: | 2348-1447 2348-229X |