The Relationship Between Dietary Intakes of Amino Acids and Bone Mineral Density Among Individuals with Spinal Cord Injury
Objectives: The effect of dietary protein intake on bone mineral density (BMD) has not been explained in patients with spinal cord injury (SCI). In this study, we looked at the relationship between BMD and higher protein intake in patients with SCI while controlling for possible confounders. Meth...
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doaj-f0d63137478c4395b5d9fffdb0050e702020-11-25T01:08:29ZengOman Medical Specialty BoardOman Medical Journal1999-768X2070-52042016-01-01311222810.5001/omj.2016.05The Relationship Between Dietary Intakes of Amino Acids and Bone Mineral Density Among Individuals with Spinal Cord InjuryHadis Sabour0Maryam Nazari1Sahar Latifi2Zahra Soltani3Hania Shakeri4Bagher Larijani5Seyed-Mohammad Ghodsi6Seyed-Hassan Emami Razavi7Brain and Spinal Cord Injury Research Center, Tehran University of Medical Sciences, Tehran, IranNutrition and Metabolic Diseases Research Center, Ahvaz Jundishapour University of Medical Sciences, Ahwaz, IranBrain and Spinal Cord Injury Research Center, Tehran University of Medical Sciences, Tehran, IranBrain and Spinal Cord Injury Research Center, Tehran University of Medical Sciences, Tehran, IranDepartment of Pathology, Shahid Beheshti University of Medical Sciences, Tehran, IranEndocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, IranBrain and Spinal Cord Injury Research Center, Tehran University of Medical Sciences, Tehran, IranBrain and Spinal Cord Injury Research Center, Tehran University of Medical Sciences, Tehran, IranObjectives: The effect of dietary protein intake on bone mineral density (BMD) has not been explained in patients with spinal cord injury (SCI). In this study, we looked at the relationship between BMD and higher protein intake in patients with SCI while controlling for possible confounders. Methods: Patients with SCI, who were referred to the Brain and Spinal Cord Injury Research Center between November 2010 and April 2012, were included in the study. In total, the dietary intakes of 103 patients were assessed by 24–hour dietary recall interviews. We used dual-energy X-ray absorptiometry to measure BMD in the femoral neck, trochanter, intertrochanteric zone, hip, and lumbar vertebras. Results: Eighty-six men and 17 women participated in this study. Protein intake was negatively associated with the BMD of lumbar vertebrae (p = 0.001, r = –0.37 for T-score and p = 0.030, r = –0.24 for Z-score). The BMD of lumbar vertebrae were negatively associated with intake of tryptophan, isoleucine, lysine, cysteine, and tyrosine (p = 0.007, 0.005, 0.009, 0.008, and 0.008 for T-score, respectively). Higher intakes of threonine, leucine, methionine, phenylalanine, valine, and histidine were related to a lower BMD of lumbar vertebrae (p = 0.006, 0.010, 0.009, 0.010, 0.009, and 0.008 respectively for T-scores). Conclusions: We found that high protein intake led to a lower BMD of lumbar vertebrae in patients with SCI after controlling for confounders including demographic and injury-related characteristics and calcium intake. No relationship between higher amino acids intake and BMD of the femur and hip was detected. Intake of alanine, arginine, and aspartic acid were not related to BMD.http://www.omjournal.org/fultext_PDF.aspx?DetailsID=724&type=fultextSpinal Cord InjuriesDietBone DensityProteinAmino Acids |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Hadis Sabour Maryam Nazari Sahar Latifi Zahra Soltani Hania Shakeri Bagher Larijani Seyed-Mohammad Ghodsi Seyed-Hassan Emami Razavi |
spellingShingle |
Hadis Sabour Maryam Nazari Sahar Latifi Zahra Soltani Hania Shakeri Bagher Larijani Seyed-Mohammad Ghodsi Seyed-Hassan Emami Razavi The Relationship Between Dietary Intakes of Amino Acids and Bone Mineral Density Among Individuals with Spinal Cord Injury Oman Medical Journal Spinal Cord Injuries Diet Bone Density Protein Amino Acids |
author_facet |
Hadis Sabour Maryam Nazari Sahar Latifi Zahra Soltani Hania Shakeri Bagher Larijani Seyed-Mohammad Ghodsi Seyed-Hassan Emami Razavi |
author_sort |
Hadis Sabour |
title |
The Relationship Between Dietary Intakes of Amino Acids and Bone Mineral Density Among Individuals with Spinal Cord Injury |
title_short |
The Relationship Between Dietary Intakes of Amino Acids and Bone Mineral Density Among Individuals with Spinal Cord Injury |
title_full |
The Relationship Between Dietary Intakes of Amino Acids and Bone Mineral Density Among Individuals with Spinal Cord Injury |
title_fullStr |
The Relationship Between Dietary Intakes of Amino Acids and Bone Mineral Density Among Individuals with Spinal Cord Injury |
title_full_unstemmed |
The Relationship Between Dietary Intakes of Amino Acids and Bone Mineral Density Among Individuals with Spinal Cord Injury |
title_sort |
relationship between dietary intakes of amino acids and bone mineral density among individuals with spinal cord injury |
publisher |
Oman Medical Specialty Board |
series |
Oman Medical Journal |
issn |
1999-768X 2070-5204 |
publishDate |
2016-01-01 |
description |
Objectives: The effect of dietary protein intake on bone mineral density (BMD) has not been explained in patients with spinal cord injury (SCI). In this study, we looked at the relationship between BMD and higher protein intake in patients with SCI while controlling for possible confounders.
Methods: Patients with SCI, who were referred to the Brain and Spinal Cord Injury Research Center between November 2010 and April 2012, were included in the study. In total, the dietary intakes of 103 patients were assessed by 24–hour dietary recall interviews. We used dual-energy X-ray absorptiometry to measure BMD in the femoral neck, trochanter, intertrochanteric zone, hip, and lumbar vertebras.
Results: Eighty-six men and 17 women participated in this study. Protein intake was negatively associated with the BMD of lumbar vertebrae (p = 0.001, r = –0.37 for T-score and p = 0.030, r = –0.24 for Z-score). The BMD of lumbar vertebrae were negatively associated with intake of tryptophan, isoleucine, lysine, cysteine, and tyrosine (p = 0.007, 0.005, 0.009, 0.008, and 0.008 for T-score, respectively). Higher intakes of threonine, leucine, methionine, phenylalanine, valine, and histidine were related to a lower BMD of lumbar vertebrae (p = 0.006, 0.010, 0.009, 0.010, 0.009, and 0.008 respectively for T-scores).
Conclusions: We found that high protein intake led to a lower BMD of lumbar vertebrae in patients with SCI after controlling for confounders including demographic and injury-related characteristics and calcium intake. No relationship between higher amino acids intake and BMD of the femur and hip was detected. Intake of alanine, arginine, and aspartic acid were not related to BMD. |
topic |
Spinal Cord Injuries Diet Bone Density Protein Amino Acids |
url |
http://www.omjournal.org/fultext_PDF.aspx?DetailsID=724&type=fultext |
work_keys_str_mv |
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