| Summary: | This study evaluated the effects of the differences in the printing directions of stereolithography (SLA) three-dimensional (3D)-printed dentures on accuracy (trueness and precision). The maxillary denture was designed using computer-aided design (CAD) software with an STL file (master data) as the output. Three different printing directions (0°, 45°, and 90°) were used. Photopolymer resin was 3D-printed (n = 6/group). After scanning all dentures, the scanning data were saved/output as STL files (experimental data). For trueness, the experimental data were superimposed on the master data sets. For precision, the experimental data were selected from six dentures with three different printing directions and superimposed. The root mean square error (RMSE) and color map data were obtained using a deviation analysis. The averages of the RMSE values of trueness and precision at 0°, 45°, and 90° were statistically compared. The RMSE of trueness and precision were lowest at 45°, followed by 90°; the highest occurred at 0°. The RMSE of trueness and precision were significantly different among all printing directions (<i>p</i> < 0.05). The highest trueness and precision and the most favorable surface adaptation occurred when the printing direction was 45°; therefore, this may be the most effective direction for manufacturing SLA 3D-printed dentures.
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