A feasibility study of using a 3D-printed tumor model scintillator to verify the energy absorbed to a tumor
The authors developed a volumetric dosimetry detector system using in-house 3D-printable plastic scintillator resins. Three tumor model scintillators (TMSs) were developed using magnetic resonance images of a tumor. The detector system consisted of a TMS, an optical fiber, a photomultiplier tube, an...
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doaj-f131ac37017f4adea4d5fae6461bb3a72021-07-17T04:32:49ZengElsevierNuclear Engineering and Technology1738-57332021-09-0153930183025A feasibility study of using a 3D-printed tumor model scintillator to verify the energy absorbed to a tumorTae Hoon Kim0Sangmin Lee1Dong Geon Kim2Jae Young Jeong3Hye Jeong Yang4Thomas Schaarschmidt5Sang Hyoun Choi6Gyu-Seok Cho7Yong Kyun Kim8Hyun-Tai Chung9Department of Nuclear Engineering, Hanyang University College of Engineering, Seoul, Republic of KoreaDepartment of Nuclear Engineering, Hanyang University College of Engineering, Seoul, Republic of KoreaDepartment of Nuclear Engineering, Hanyang University College of Engineering, Seoul, Republic of KoreaDepartment of Nuclear Engineering, Hanyang University College of Engineering, Seoul, Republic of KoreaDepartment of Biomedicine and Health Sciences & Biomedical Engineering, Catholic University College of Medicine, Seoul, Republic of KoreaDepartment of Biomedicine and Health Sciences & Biomedical Engineering, Catholic University College of Medicine, Seoul, Republic of KoreaResearch Team of Radiological Physics and Engineering, Korea Institute of Radiological & Medical Science, Seoul, Republic of KoreaResearch Team of Radiological Physics and Engineering, Korea Institute of Radiological & Medical Science, Seoul, Republic of KoreaDepartment of Nuclear Engineering, Hanyang University College of Engineering, Seoul, Republic of Korea; Corresponding author. Hanyang University College of Engineering, Seoul, Republic of Korea.Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Republic of Korea; Corresponding author. Seoul National University College of Medicine, Seoul, Republic of Korea.The authors developed a volumetric dosimetry detector system using in-house 3D-printable plastic scintillator resins. Three tumor model scintillators (TMSs) were developed using magnetic resonance images of a tumor. The detector system consisted of a TMS, an optical fiber, a photomultiplier tube, and an electrometer. The background signal, including the Cherenkov lights generated in the optical fiber, was subtracted from the output signal. The system showed 2.1% instability when the TMS was reassembled. The system efficiencies in collecting lights for a given absorbed energy were determined by calibration at a secondary standard dosimetry laboratory (kSSDL) or by calibration using Monte Carlo simulations (ksim). The TMSs were irradiated in a Gamma Knife® Icon™ (Elekta AB, Stockholm, Sweden) following a treatment plan. The energies absorbed to the TMSs were measured and compared with a calculated value. While the measured energy determined with kSSDL was (5.84 ± 3.56) % lower than the calculated value, the energy with ksim was (2.00 ± 0.76) % higher. Although the TMS detector system worked reasonably well in measuring the absorbed energy to a tumor, further improvements in the calibration procedure and system stability are needed for the system to be accepted as a quality assurance tool.http://www.sciencedirect.com/science/article/pii/S17385733210017773D-printed tumor modelPlastic scintillatorAbsorbed energyVolumetric dosimetryTreatment planning systemMonte Carlo simulation |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Tae Hoon Kim Sangmin Lee Dong Geon Kim Jae Young Jeong Hye Jeong Yang Thomas Schaarschmidt Sang Hyoun Choi Gyu-Seok Cho Yong Kyun Kim Hyun-Tai Chung |
spellingShingle |
Tae Hoon Kim Sangmin Lee Dong Geon Kim Jae Young Jeong Hye Jeong Yang Thomas Schaarschmidt Sang Hyoun Choi Gyu-Seok Cho Yong Kyun Kim Hyun-Tai Chung A feasibility study of using a 3D-printed tumor model scintillator to verify the energy absorbed to a tumor Nuclear Engineering and Technology 3D-printed tumor model Plastic scintillator Absorbed energy Volumetric dosimetry Treatment planning system Monte Carlo simulation |
author_facet |
Tae Hoon Kim Sangmin Lee Dong Geon Kim Jae Young Jeong Hye Jeong Yang Thomas Schaarschmidt Sang Hyoun Choi Gyu-Seok Cho Yong Kyun Kim Hyun-Tai Chung |
author_sort |
Tae Hoon Kim |
title |
A feasibility study of using a 3D-printed tumor model scintillator to verify the energy absorbed to a tumor |
title_short |
A feasibility study of using a 3D-printed tumor model scintillator to verify the energy absorbed to a tumor |
title_full |
A feasibility study of using a 3D-printed tumor model scintillator to verify the energy absorbed to a tumor |
title_fullStr |
A feasibility study of using a 3D-printed tumor model scintillator to verify the energy absorbed to a tumor |
title_full_unstemmed |
A feasibility study of using a 3D-printed tumor model scintillator to verify the energy absorbed to a tumor |
title_sort |
feasibility study of using a 3d-printed tumor model scintillator to verify the energy absorbed to a tumor |
publisher |
Elsevier |
series |
Nuclear Engineering and Technology |
issn |
1738-5733 |
publishDate |
2021-09-01 |
description |
The authors developed a volumetric dosimetry detector system using in-house 3D-printable plastic scintillator resins. Three tumor model scintillators (TMSs) were developed using magnetic resonance images of a tumor. The detector system consisted of a TMS, an optical fiber, a photomultiplier tube, and an electrometer. The background signal, including the Cherenkov lights generated in the optical fiber, was subtracted from the output signal. The system showed 2.1% instability when the TMS was reassembled. The system efficiencies in collecting lights for a given absorbed energy were determined by calibration at a secondary standard dosimetry laboratory (kSSDL) or by calibration using Monte Carlo simulations (ksim). The TMSs were irradiated in a Gamma Knife® Icon™ (Elekta AB, Stockholm, Sweden) following a treatment plan. The energies absorbed to the TMSs were measured and compared with a calculated value. While the measured energy determined with kSSDL was (5.84 ± 3.56) % lower than the calculated value, the energy with ksim was (2.00 ± 0.76) % higher. Although the TMS detector system worked reasonably well in measuring the absorbed energy to a tumor, further improvements in the calibration procedure and system stability are needed for the system to be accepted as a quality assurance tool. |
topic |
3D-printed tumor model Plastic scintillator Absorbed energy Volumetric dosimetry Treatment planning system Monte Carlo simulation |
url |
http://www.sciencedirect.com/science/article/pii/S1738573321001777 |
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