MicroRNA-Mediated Gene Silencing in Plant Defense and Viral Counter-Defense
MicroRNAs (miRNAs) are non-coding RNAs of approximately 20–24 nucleotides in length that serve as central regulators of eukaryotic gene expression by targeting mRNAs for cleavage or translational repression. In plants, miRNAs are associated with numerous regulatory pathways in growth and development...
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doaj-f1358e94aabd45dd9f5fe705f82571852020-11-24T21:08:57ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2017-09-01810.3389/fmicb.2017.01801283608MicroRNA-Mediated Gene Silencing in Plant Defense and Viral Counter-DefenseSheng-Rui Liu0Jing-Jing Zhou1Chun-Gen Hu2Chao-Ling Wei3Jin-Zhi Zhang4State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural UniversityHefei, ChinaCollege of Horticulture and Forestry Sciences, Huazhong Agricultural UniversityWuhan, ChinaKey Laboratory of Horticultural Plant Biology (Ministry of Education), College of Horticulture and Forestry Sciences, Huazhong Agricultural UniversityWuhan, ChinaState Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural UniversityHefei, ChinaKey Laboratory of Horticultural Plant Biology (Ministry of Education), College of Horticulture and Forestry Sciences, Huazhong Agricultural UniversityWuhan, ChinaMicroRNAs (miRNAs) are non-coding RNAs of approximately 20–24 nucleotides in length that serve as central regulators of eukaryotic gene expression by targeting mRNAs for cleavage or translational repression. In plants, miRNAs are associated with numerous regulatory pathways in growth and development processes, and defensive responses in plant–pathogen interactions. Recently, significant progress has been made in understanding miRNA-mediated gene silencing and how viruses counter this defense mechanism. Here, we summarize the current knowledge and recent advances in understanding the roles of miRNAs involved in the plant defense against viruses and viral counter-defense. We also document the application of miRNAs in plant antiviral defense. This review discusses the current understanding of the mechanisms of miRNA-mediated gene silencing and provides insights on the never-ending arms race between plants and viruses.http://journal.frontiersin.org/article/10.3389/fmicb.2017.01801/fulldefensecounter-defensegene silencingmiRNAvirus |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sheng-Rui Liu Jing-Jing Zhou Chun-Gen Hu Chao-Ling Wei Jin-Zhi Zhang |
spellingShingle |
Sheng-Rui Liu Jing-Jing Zhou Chun-Gen Hu Chao-Ling Wei Jin-Zhi Zhang MicroRNA-Mediated Gene Silencing in Plant Defense and Viral Counter-Defense Frontiers in Microbiology defense counter-defense gene silencing miRNA virus |
author_facet |
Sheng-Rui Liu Jing-Jing Zhou Chun-Gen Hu Chao-Ling Wei Jin-Zhi Zhang |
author_sort |
Sheng-Rui Liu |
title |
MicroRNA-Mediated Gene Silencing in Plant Defense and Viral Counter-Defense |
title_short |
MicroRNA-Mediated Gene Silencing in Plant Defense and Viral Counter-Defense |
title_full |
MicroRNA-Mediated Gene Silencing in Plant Defense and Viral Counter-Defense |
title_fullStr |
MicroRNA-Mediated Gene Silencing in Plant Defense and Viral Counter-Defense |
title_full_unstemmed |
MicroRNA-Mediated Gene Silencing in Plant Defense and Viral Counter-Defense |
title_sort |
microrna-mediated gene silencing in plant defense and viral counter-defense |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Microbiology |
issn |
1664-302X |
publishDate |
2017-09-01 |
description |
MicroRNAs (miRNAs) are non-coding RNAs of approximately 20–24 nucleotides in length that serve as central regulators of eukaryotic gene expression by targeting mRNAs for cleavage or translational repression. In plants, miRNAs are associated with numerous regulatory pathways in growth and development processes, and defensive responses in plant–pathogen interactions. Recently, significant progress has been made in understanding miRNA-mediated gene silencing and how viruses counter this defense mechanism. Here, we summarize the current knowledge and recent advances in understanding the roles of miRNAs involved in the plant defense against viruses and viral counter-defense. We also document the application of miRNAs in plant antiviral defense. This review discusses the current understanding of the mechanisms of miRNA-mediated gene silencing and provides insights on the never-ending arms race between plants and viruses. |
topic |
defense counter-defense gene silencing miRNA virus |
url |
http://journal.frontiersin.org/article/10.3389/fmicb.2017.01801/full |
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