Propofol inhibits stromatoxin-1-sensitive voltage-dependent K+ channels in pancreatic β-cells and enhances insulin secretion

Propofol inhibits stromatoxin-1-sensitive voltage-dependent K+ channels in pancreatic β-cells and enhances insulin secretion

Background Proper glycemic control is an important goal of critical care medicine, including perioperative patient care that can influence patients’ prognosis. Insulin secretion from pancreatic β-cells is generally assumed to play a critical role in glycemic control in response to an elevated blood...

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Bibliographic Details
Main Authors: Munenori Kusunoki, Mikio Hayashi, Tomohiro Shoji, Takeo Uba, Hiromasa Tanaka, Chisato Sumi, Yoshiyuki Matsuo, Kiichi Hirota
Format: Article
Language:English
Published: PeerJ Inc. 2019-12-01
Series:PeerJ
Subjects:
Insulin
Pancreatic β-cells
Propofol
Kv channel
Stromatoxin-1
Anesthetic
Online Access:https://peerj.com/articles/8157.pdf

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