Trypanosoma cruzi and experimental Chagas' disease: characterization of a stock isolated from a patient with associated digestive and cardiac form
A new Trypanosoma cruzi stock isolated from a patient in the chronic phase of Chagas' disease with the digestive and cardiac fortn of the disease was characterized by experimental infection in isogenic, susceptible, A/Sn strain mice. Parasitemia curves showed up to 1.7x10(6) parasites/ml and no...
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Sociedade Brasileira de Medicina Tropical (SBMT)
1993-03-01
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doaj-f14a8eb538104cd9ba90724e3319143a2020-11-25T00:19:19ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98491993-03-01261253310.1590/S0037-86821993000100006S0037-86821993000100006Trypanosoma cruzi and experimental Chagas' disease: characterization of a stock isolated from a patient with associated digestive and cardiac formE.C. OliveiraM.M.A. StefaniA.O. LuquettiE.F. VêncioM.A.R. MoreiraC. SouzaJ.M. RezendeA new Trypanosoma cruzi stock isolated from a patient in the chronic phase of Chagas' disease with the digestive and cardiac fortn of the disease was characterized by experimental infection in isogenic, susceptible, A/Sn strain mice. Parasitemia curves showed up to 1.7x10(6) parasites/ml and no mortality was observed up to 300 days post infection. Specific IgM was found in mice in the acute phase up to 40 days and also in the chronic phase. IgG antibodies yvere detected in the acute and chronic phase. Histopathology examination demonstrated myotropism to the digestive tract muscle layers and to the heart.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821993000100006&lng=en&tlng=enCepa de Trypanosoma cruziDoença de ChagasInfecção experimentalSorologiaHistopatologia |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
E.C. Oliveira M.M.A. Stefani A.O. Luquetti E.F. Vêncio M.A.R. Moreira C. Souza J.M. Rezende |
spellingShingle |
E.C. Oliveira M.M.A. Stefani A.O. Luquetti E.F. Vêncio M.A.R. Moreira C. Souza J.M. Rezende Trypanosoma cruzi and experimental Chagas' disease: characterization of a stock isolated from a patient with associated digestive and cardiac form Revista da Sociedade Brasileira de Medicina Tropical Cepa de Trypanosoma cruzi Doença de Chagas Infecção experimental Sorologia Histopatologia |
author_facet |
E.C. Oliveira M.M.A. Stefani A.O. Luquetti E.F. Vêncio M.A.R. Moreira C. Souza J.M. Rezende |
author_sort |
E.C. Oliveira |
title |
Trypanosoma cruzi and experimental Chagas' disease: characterization of a stock isolated from a patient with associated digestive and cardiac form |
title_short |
Trypanosoma cruzi and experimental Chagas' disease: characterization of a stock isolated from a patient with associated digestive and cardiac form |
title_full |
Trypanosoma cruzi and experimental Chagas' disease: characterization of a stock isolated from a patient with associated digestive and cardiac form |
title_fullStr |
Trypanosoma cruzi and experimental Chagas' disease: characterization of a stock isolated from a patient with associated digestive and cardiac form |
title_full_unstemmed |
Trypanosoma cruzi and experimental Chagas' disease: characterization of a stock isolated from a patient with associated digestive and cardiac form |
title_sort |
trypanosoma cruzi and experimental chagas' disease: characterization of a stock isolated from a patient with associated digestive and cardiac form |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
series |
Revista da Sociedade Brasileira de Medicina Tropical |
issn |
1678-9849 |
publishDate |
1993-03-01 |
description |
A new Trypanosoma cruzi stock isolated from a patient in the chronic phase of Chagas' disease with the digestive and cardiac fortn of the disease was characterized by experimental infection in isogenic, susceptible, A/Sn strain mice. Parasitemia curves showed up to 1.7x10(6) parasites/ml and no mortality was observed up to 300 days post infection. Specific IgM was found in mice in the acute phase up to 40 days and also in the chronic phase. IgG antibodies yvere detected in the acute and chronic phase. Histopathology examination demonstrated myotropism to the digestive tract muscle layers and to the heart. |
topic |
Cepa de Trypanosoma cruzi Doença de Chagas Infecção experimental Sorologia Histopatologia |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821993000100006&lng=en&tlng=en |
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