Alpha-Synuclein Pathology Coincides With Increased Number of Early Stage Neural Progenitors in the Adult Hippocampus
Alpha-synuclein pathology driven impairment in adult neurogenesis was proposed as a potential cause of, or at least contributor to, memory impairment observed in both patients and animal models of Parkinson’s disease (PD) and Dementia with Lewy Bodies (DLB). Mice overexpressing wild-type alpha-synuc...
Main Authors: | Hannah Bender, Simone A. Fietz, Franziska Richter, Milos Stanojlovic |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-07-01
|
Series: | Frontiers in Cell and Developmental Biology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2021.691560/full |
Similar Items
-
Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies
by: Attems, J., et al.
Published: (2022) -
Possible Role of Amyloidogenic Evolvability in Dementia with Lewy Bodies: Insights from Transgenic Mice Expressing P123H β-Synuclein
by: Masayo Fujita, et al.
Published: (2020-04-01) -
Amyloid-Beta Peptides Trigger Aggregation of Alpha-Synuclein In Vitro
by: Janett Köppen, et al.
Published: (2020-01-01) -
Trans-synaptic and retrograde axonal spread of Lewy pathology following pre-formed fibril injection in an in vivo A53T alpha-synuclein mouse model of synucleinopathy
by: Allison J. Schaser, et al.
Published: (2020-08-01) -
Alpha-Synuclein Post-translational Modifications: Implications for Pathogenesis of Lewy Body Disorders
by: Nelson de Oliveira Manzanza, et al.
Published: (2021-06-01)