Biological Effectiveness of Accelerated Protons for Chromosome Exchanges

We have investigated chromosome exchanges induced in human cells by 7 different energies of protons (5 MeV to 2.5 GeV) with LET values ranging from 0.2 to 8 keV/m. Human lymphocytes were irradiated in vitro and chromosome damage was assessed using three-color fluorescence in situ hybridization (FIS...

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Bibliographic Details
Main Author: Kerry eGeorge
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Oncology
Subjects:
RBE
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00226/full