EFFECT OF BISPHENOL - A ON IMMUNE SYSTEM OF WISTAR RATS
A sub-acute toxicity study of Bisphenol A (BPA) was conducted on Wister rat to investigate its potency and impact on mammals. The doses chosen were 50, 200 and 600 mg/kg body weight for group III, IV and V respectively and group II served as vehicle control and group I was negative control. BPA c...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
West Bengal Veterinary Alumni Association
2016-06-01
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| Series: | Exploratory Animal and Medical Research |
| Subjects: | |
| Online Access: | http://www.animalmedicalresearch.org/Vol.6_Issue-1_June_2016/S%20S%20Karnam.pdf |
| Summary: | A sub-acute toxicity study of Bisphenol A (BPA) was conducted on Wister rat to investigate
its potency and impact on mammals. The doses chosen were 50, 200 and 600 mg/kg body weight for
group III, IV and V respectively and group II served as vehicle control and group I was negative
control. BPA caused significant (P < 0.01) decrease in humoral immune response to sheep red blood
cell as antigen (SRBC) in group V and significant (P < 0.01) depression of cell mediated immunity
(CMI) were obserevd in BPA treated rats as measured by dinitrofluorobenzene (DNFB) skin contact
sensitization test. |
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| ISSN: | 2277-470X 2319-247X |