Recombination and lineage-specific mutations linked to the emergence of SARS-CoV-2

Recombination and lineage-specific mutations linked to the emergence of SARS-CoV-2

Abstract Background The emergence of SARS-CoV-2 underscores the need to better understand the evolutionary processes that drive the emergence and adaptation of zoonotic viruses in humans. In the betacoronavirus genus, which also includes SARS-CoV and MERS-CoV, recombination frequently encompasses th...

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Bibliographic Details
Main Authors: Juan Ángel Patiño-Galindo, Ioan Filip, Ratul Chowdhury, Costas D. Maranas, Peter K. Sorger, Mohammed AlQuraishi, Raul Rabadan
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Genome Medicine
Subjects:
SARS-CoV-2
Recombination
Receptor binding affinity
Zoonosis
Online Access:https://doi.org/10.1186/s13073-021-00943-6

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