MicroRNA-10a is down-regulated by DNA methylation and functions as a tumor suppressor in gastric cancer cells.
BACKGROUND: MicroRNAs act as posttranscriptional regulators of gene expression in many biological processes. Their deregulations occur commonly in gastric cancer (GC). Although DNA methylation constitutes an important mechanism for microRNA deregulation in cancer, this field largely remains unexplor...
Main Authors: | Hongyan Jia, Zhengyi Zhang, Dongling Zou, Bin Wang, Yunmeng Yan, Min Luo, Lei Dong, Haixin Yin, Bei Gong, Zheng Li, Fang Wang, Wei Song, Changzheng Liu, Yanni Ma, Junwu Zhang, Haoliang Zhao, Jianxiong Li, Jia Yu |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3909310?pdf=render |
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