Cyclic-AMP mediated regulation of ABCB mRNA expression in mussel haemocytes.

The multixenobiotic resistance system (MXR) allows aquatic organisms to cope with their habitat despite high pollution levels by over-expressing membrane and intracellular transporters, including the P-glycoprotein (Pgp). In mammals transcription of the ABCB1 gene encoding Pgp is under cAMP/PKA-medi...

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Bibliographic Details
Main Authors: Silvia Franzellitti, Elena Fabbri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3625153?pdf=render

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