Factors associated with multi-drug-resistant tuberculosis in Dakar, Senegal, 2010-2016
According to the World Health Organization, multidrug-resistant tuberculosis (MDR-TB) represents a major obstacle towards successful TB treatment and control. In Dakar, MDR-TB management began in 2010 with the strengthening of diagnostic resources. The objective of this study was to identify the fa...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
PAGEPress Publications
2020-03-01
|
Series: | Journal of Public Health in Africa |
Subjects: | |
Online Access: | https://www.publichealthinafrica.org/index.php/jphia/article/view/1099 |
id |
doaj-f1ddddcf2d764a8a985a63c3ad3fcd12 |
---|---|
record_format |
Article |
spelling |
doaj-f1ddddcf2d764a8a985a63c3ad3fcd122020-11-25T03:10:23ZengPAGEPress PublicationsJournal of Public Health in Africa2038-99222038-99302020-03-0110210.4081/jphia.2019.1099Factors associated with multi-drug-resistant tuberculosis in Dakar, Senegal, 2010-2016Mbouna Ndiaye0Pauline Kiswendsida Yanogo1Bernard Sawadogo2Fadima Diallo3Simon Antara4Nicolas Meda5West Africa Field Epidemiology Training Program (WAFETP)West Africa Field Epidemiology Training Program (WAFETP), and Faculty of Medicine, University Ouaga 1, Professor Joseph Ki-zerboWest Africa Field Epidemiology Training Programme (WAFETP)West Africa Field Epidemiology Training Programme (WAFETP)West Africa Field Epidemiology Training Programme (WAFETP)West Africa Field Epidemiology Training Program (WAFETP), and 2aculty of Medicine, University Ouaga 1, Professor Joseph Ki-zerbo According to the World Health Organization, multidrug-resistant tuberculosis (MDR-TB) represents a major obstacle towards successful TB treatment and control. In Dakar, MDR-TB management began in 2010 with the strengthening of diagnostic resources. The objective of this study was to identify the factors associated with multidrug-resistant tuberculosis in Dakar between 2010 and 2016. We conducted a case-control study from January 10 to February 28, 2017 in tuberculosis centers in Dakar. of 169 cases and 507 controls. We used logistic regression with Epi-info version 7.2.1. to estimate the odds ratios of association. Factors significantly associated with MDR-TB were: residing in a periurban area (ORa=1.8; 95% CI (1.5-4.9); p=0.024), presence of MDR-TB in the entourage of patient (ORa=7.0; 95% CI (6.1-9.5); p=0.002), previous treatment failure (ORa=29.5; 95% CI (27.3-30.1); p=0.000), treatment not directly observed by a health care provider (ORa=4.3; 95% CI (4.1-7,2); p=0.000) and irregularity of treatment (ORa=1.7; 95% CI (0.5-5.4); p=0.037). Focusing interventions on population at-risk will prevent MDR-TB. https://www.publichealthinafrica.org/index.php/jphia/article/view/1099multidrug-resistant tuberculosisfactorsDakar |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mbouna Ndiaye Pauline Kiswendsida Yanogo Bernard Sawadogo Fadima Diallo Simon Antara Nicolas Meda |
spellingShingle |
Mbouna Ndiaye Pauline Kiswendsida Yanogo Bernard Sawadogo Fadima Diallo Simon Antara Nicolas Meda Factors associated with multi-drug-resistant tuberculosis in Dakar, Senegal, 2010-2016 Journal of Public Health in Africa multidrug-resistant tuberculosis factors Dakar |
author_facet |
Mbouna Ndiaye Pauline Kiswendsida Yanogo Bernard Sawadogo Fadima Diallo Simon Antara Nicolas Meda |
author_sort |
Mbouna Ndiaye |
title |
Factors associated with multi-drug-resistant tuberculosis in Dakar, Senegal, 2010-2016 |
title_short |
Factors associated with multi-drug-resistant tuberculosis in Dakar, Senegal, 2010-2016 |
title_full |
Factors associated with multi-drug-resistant tuberculosis in Dakar, Senegal, 2010-2016 |
title_fullStr |
Factors associated with multi-drug-resistant tuberculosis in Dakar, Senegal, 2010-2016 |
title_full_unstemmed |
Factors associated with multi-drug-resistant tuberculosis in Dakar, Senegal, 2010-2016 |
title_sort |
factors associated with multi-drug-resistant tuberculosis in dakar, senegal, 2010-2016 |
publisher |
PAGEPress Publications |
series |
Journal of Public Health in Africa |
issn |
2038-9922 2038-9930 |
publishDate |
2020-03-01 |
description |
According to the World Health Organization, multidrug-resistant tuberculosis (MDR-TB) represents a major obstacle towards successful TB treatment and control. In Dakar, MDR-TB management began in 2010 with the strengthening of diagnostic resources. The objective of this study was to identify the factors associated with multidrug-resistant tuberculosis in Dakar between 2010 and 2016. We conducted a case-control study from January 10 to February 28, 2017 in tuberculosis centers in Dakar. of 169 cases and 507 controls. We used logistic regression with Epi-info version 7.2.1. to estimate the odds ratios of association. Factors significantly associated with MDR-TB were: residing in a periurban area (ORa=1.8; 95% CI (1.5-4.9); p=0.024), presence of MDR-TB in the entourage of patient (ORa=7.0; 95% CI (6.1-9.5); p=0.002), previous treatment failure (ORa=29.5; 95% CI (27.3-30.1); p=0.000), treatment not directly observed by a health care provider (ORa=4.3; 95% CI (4.1-7,2); p=0.000) and irregularity of treatment (ORa=1.7; 95% CI (0.5-5.4); p=0.037). Focusing interventions on population at-risk will prevent MDR-TB.
|
topic |
multidrug-resistant tuberculosis factors Dakar |
url |
https://www.publichealthinafrica.org/index.php/jphia/article/view/1099 |
work_keys_str_mv |
AT mbounandiaye factorsassociatedwithmultidrugresistanttuberculosisindakarsenegal20102016 AT paulinekiswendsidayanogo factorsassociatedwithmultidrugresistanttuberculosisindakarsenegal20102016 AT bernardsawadogo factorsassociatedwithmultidrugresistanttuberculosisindakarsenegal20102016 AT fadimadiallo factorsassociatedwithmultidrugresistanttuberculosisindakarsenegal20102016 AT simonantara factorsassociatedwithmultidrugresistanttuberculosisindakarsenegal20102016 AT nicolasmeda factorsassociatedwithmultidrugresistanttuberculosisindakarsenegal20102016 |
_version_ |
1724658996706541568 |