A novel fusogenic herpes simplex virus for oncolytic virotherapy of squamous cell carcinoma
<p>Abstract</p> <p>Background</p> <p>R849 is a neurovirulent γ<sub>1</sub>34.5 gene-deficient form of herpes simplex virus type 1 (HSV-1) and has LacZ genes at the deleted sites of the γ<sub>1</sub>34.5 gene. HF is a spontaneously occurring, fuso...
Main Authors: | Iwai Soichi, Imai Tomoaki, Ogawa Fumi, Takahashi Gen, Takaoka Hiroo, Yura Yoshiaki |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-06-01
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Series: | Virology Journal |
Subjects: | |
Online Access: | http://www.virologyj.com/content/8/1/294 |
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